Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health

Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced p...

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Detalles Bibliográficos
Autores principales: Halvaei, Iman, Litzky, Julia, Esfandiari, Navid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664076/
https://www.ncbi.nlm.nih.gov/pubmed/33183337
http://dx.doi.org/10.1186/s12958-020-00668-y
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author Halvaei, Iman
Litzky, Julia
Esfandiari, Navid
author_facet Halvaei, Iman
Litzky, Julia
Esfandiari, Navid
author_sort Halvaei, Iman
collection PubMed
description Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced paternal age on sperm quality, assisted reproductive outcomes, and the health of the offspring conceived by older fathers. This review discusses the association between advanced paternal age and sperm parameters, assisted reproduction success rates, and offspring health.
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spelling pubmed-76640762020-11-13 Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health Halvaei, Iman Litzky, Julia Esfandiari, Navid Reprod Biol Endocrinol Review Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced paternal age on sperm quality, assisted reproductive outcomes, and the health of the offspring conceived by older fathers. This review discusses the association between advanced paternal age and sperm parameters, assisted reproduction success rates, and offspring health. BioMed Central 2020-11-13 /pmc/articles/PMC7664076/ /pubmed/33183337 http://dx.doi.org/10.1186/s12958-020-00668-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Halvaei, Iman
Litzky, Julia
Esfandiari, Navid
Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
title Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
title_full Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
title_fullStr Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
title_full_unstemmed Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
title_short Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
title_sort advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664076/
https://www.ncbi.nlm.nih.gov/pubmed/33183337
http://dx.doi.org/10.1186/s12958-020-00668-y
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