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LINC00973 Induces Proliferation Arrest of Drug-Treated Cancer Cells by Preventing p21 Degradation

Overcoming drug resistance of cancer cells is the major challenge in molecular oncology. Here, we demonstrate that long non-coding RNA LINC00973 is up-regulated in normal and cancer cells of different origins upon treatment with different chemotherapeutics. Bioinformatics analysis shows that this is...

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Detalles Bibliográficos
Autores principales: Karpov, Dmitry S., Spirin, Pavel V., Zheltukhin, Andrey O., Tutyaeva, Vera V., Zinovieva, Olga L., Grineva, Evgenia N., Matrosova, Vera A., Krasnov, George S., Snezhkina, Anastasiya V., Kudryavtseva, Anna V., Prassolov, Vladimir S., Mashkova, Tamara D., Lisitsyn, Nikolai A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664178/
https://www.ncbi.nlm.nih.gov/pubmed/33171937
http://dx.doi.org/10.3390/ijms21218322

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