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Mass Spectrometry-Based Solid Phase Peptide Reaction Assay for Detecting Allergenicity Using an Immobilized Peptide-Conjugating Photo-Cleavable Linker
The biological process of skin sensitization depends on the ability of a sensitizer to modify endogenous proteins. A direct peptide reactivity assay (DPRA), based on the biological process of skin sensitization, was developed as an alternative to controversial animal experiments. Although DPRA has b...
Autores principales: | Miyazaki, Hiroshi, Samejima, Yasutaka, Iwata, Kazuya, Minamino, Yuuki, Hikida, Shinya, Ariumi, Hideto, Ikeda, Hidefumi, Hamada, Yoshio, Yamashita, Kunihiko, Usui, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664224/ https://www.ncbi.nlm.nih.gov/pubmed/33172037 http://dx.doi.org/10.3390/ijms21218332 |
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