The Cytogenomic “Theory of Everything”: Chromohelkosis May Underlie Chromosomal Instability and Mosaicism in Disease and Aging

Mechanisms for somatic chromosomal mosaicism (SCM) and chromosomal instability (CIN) are not completely understood. During molecular karyotyping and bioinformatic analyses of children with neurodevelopmental disorders and congenital malformations (n = 612), we observed colocalization of regular chro...

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Detalles Bibliográficos
Autores principales: Iourov, Ivan Y., Vorsanova, Svetlana G., Yurov, Yuri B., Zelenova, Maria A., Kurinnaia, Oxana S., Vasin, Kirill S., Kutsev, Sergei I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664247/
https://www.ncbi.nlm.nih.gov/pubmed/33171981
http://dx.doi.org/10.3390/ijms21218328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664247/
https://www.ncbi.nlm.nih.gov/pubmed/33171981
http://dx.doi.org/10.3390/ijms21218328

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