Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS‐275

OBJECTIVE: To assess class I‐histone deacetylase (HDAC) inhibition on formation of lipid‐accumulating, disease‐promoting phagocytes upon myelin load in vitro, relevant for neuroinflammatory disorders like multiple sclerosis (MS) and cerebral X‐linked adrenoleukodystrophy (X‐ALD). METHODS: Immunohist...

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Detalles Bibliográficos
Autores principales: Zierfuss, Bettina, Weinhofer, Isabelle, Buda, Agnieszka, Popitsch, Niko, Hess, Lena, Moos, Verena, Hametner, Simon, Kemp, Stephan, Köhler, Wolfgang, Forss‐Petter, Sonja, Seiser, Christian, Berger, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664285/
https://www.ncbi.nlm.nih.gov/pubmed/32997393
http://dx.doi.org/10.1002/acn3.51200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664285/
https://www.ncbi.nlm.nih.gov/pubmed/32997393
http://dx.doi.org/10.1002/acn3.51200

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