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Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS‐275
OBJECTIVE: To assess class I‐histone deacetylase (HDAC) inhibition on formation of lipid‐accumulating, disease‐promoting phagocytes upon myelin load in vitro, relevant for neuroinflammatory disorders like multiple sclerosis (MS) and cerebral X‐linked adrenoleukodystrophy (X‐ALD). METHODS: Immunohist...
Autores principales: | Zierfuss, Bettina, Weinhofer, Isabelle, Buda, Agnieszka, Popitsch, Niko, Hess, Lena, Moos, Verena, Hametner, Simon, Kemp, Stephan, Köhler, Wolfgang, Forss‐Petter, Sonja, Seiser, Christian, Berger, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664285/ https://www.ncbi.nlm.nih.gov/pubmed/32997393 http://dx.doi.org/10.1002/acn3.51200 |
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