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3D Spheroids Derived from Human Lipedema ASCs Demonstrated Similar Adipogenic Differentiation Potential and ECM Remodeling to Non-Lipedema ASCs In Vitro

The growth and differentiation of adipose tissue-derived stem cells (ASCs) is stimulated and regulated by the adipose tissue (AT) microenvironment. In lipedema, both inflammation and hypoxia influence the expansion and differentiation of ASCs, resulting in hypertrophic adipocytes and deposition of c...

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Detalles Bibliográficos
Autores principales: Al-Ghadban, Sara, Pursell, India A., Diaz, Zaidmara T., Herbst, Karen L., Bunnell, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664323/
https://www.ncbi.nlm.nih.gov/pubmed/33171717
http://dx.doi.org/10.3390/ijms21218350

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