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3D Spheroids Derived from Human Lipedema ASCs Demonstrated Similar Adipogenic Differentiation Potential and ECM Remodeling to Non-Lipedema ASCs In Vitro
The growth and differentiation of adipose tissue-derived stem cells (ASCs) is stimulated and regulated by the adipose tissue (AT) microenvironment. In lipedema, both inflammation and hypoxia influence the expansion and differentiation of ASCs, resulting in hypertrophic adipocytes and deposition of c...
Autores principales: | Al-Ghadban, Sara, Pursell, India A., Diaz, Zaidmara T., Herbst, Karen L., Bunnell, Bruce A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664323/ https://www.ncbi.nlm.nih.gov/pubmed/33171717 http://dx.doi.org/10.3390/ijms21218350 |
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