A novel liposome-polymer hybrid nanoparticles delivering a multi-epitope self-replication DNA vaccine and its preliminary immune evaluation in experimental animals

DNA vaccine is an attractive immune platform for the prevention and treatment of infectious diseases, but existing disadvantages limit its use in preclinical and clinical assays, such as weak immunogenicity and short half-life. Here, we reported a novel liposome-polymer hybrid nanoparticles (pSFV-ME...

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Detalles Bibliográficos
Autores principales: Zhao, Zhangting, Ma, Xingyuan, Zhang, Ruihuan, Hu, Fabiao, Zhang, Tong, Liu, Yuping, Han, Myong Hun, You, Fang, Yang, Yi, Zheng, Wenyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664365/
https://www.ncbi.nlm.nih.gov/pubmed/33197626
http://dx.doi.org/10.1016/j.nano.2020.102338

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