Biaryl Sulfonamides Based on the 2-Azabicycloalkane Skeleton—Synthesis and Antiproliferative Activity

In a search for new, selective antitumor agents, we prepared a series of sulfonamides built on bicyclic scaffolds of 2-azabicyclo(2.2.1)heptane and 2-azabicyclo(3.2.1)octane. To this end, aza-Diels–Alder cycloadducts were converted into amines bearing 2-azanorbornane or a bridged azepane skeleton; t...

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Detalles Bibliográficos
Autores principales: Iwan, Dominika, Kamińska, Karolina, Wojaczyńska, Elżbieta, Psurski, Mateusz, Wietrzyk, Joanna, Daszkiewicz, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664408/
https://www.ncbi.nlm.nih.gov/pubmed/33172089
http://dx.doi.org/10.3390/ma13215010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664408/
https://www.ncbi.nlm.nih.gov/pubmed/33172089
http://dx.doi.org/10.3390/ma13215010

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