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Combined effects on leukemia cell growth by targeting sphingosine kinase 1 and sirtuin 1 signaling

Targeting multiple signaling pathways is a potential novel therapeutic strategy for the treatment of leukemias. Leukemia cells express high levels of sphingosine kinase 1 (Sphk1) and sirtuin 1 (SIRT1). However, to the best of our knowledge, their interaction and potential synergistic inhibitory effe...

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Detalles Bibliográficos
Autores principales:	Li, Yuxiang, Gao, Yuxia, Liang, Bing, Nie, Wenbo, Zhao, Lijing, Wang, Lisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664611/ https://www.ncbi.nlm.nih.gov/pubmed/33199987 http://dx.doi.org/10.3892/etm.2020.9392

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