Cargando…

Nanomaterials for Cardiac Tissue Engineering

End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and car...

Descripción completa

Detalles Bibliográficos
Autores principales: R. Amin, Devang, Sink, Eric, Narayan, Suguna P., Abdel-Hafiz, Mostafa, Mestroni, Luisa, Peña, Brisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664640/
https://www.ncbi.nlm.nih.gov/pubmed/33171802
http://dx.doi.org/10.3390/molecules25215189
Descripción
Sumario:End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering.