Cargando…

microRNA-Based Biomarkers in Alzheimer’s Disease (AD)

Alzheimer’s disease (AD) is a multifactorial, age-related neurological disease characterized by complex pathophysiological dynamics taking place at multiple biological levels, including molecular, genetic, epigenetic, cellular and large-scale brain networks. These alterations account for multiple pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Yuhai, Jaber, Vivian, Alexandrov, Peter N., Vergallo, Andrea, Lista, Simone, Hampel, Harald, Lukiw, Walter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664832/ https://www.ncbi.nlm.nih.gov/pubmed/33192270 http://dx.doi.org/10.3389/fnins.2020.585432

Ejemplares similares

Biomarkers for Alzheimer’s Disease (AD) and the Application of Precision Medicine
por: Lukiw, Walter J., et al.
Publicado: (2020)

microRNA-Based Biomarkers and the Diagnosis of Alzheimer’s Disease
por: Zhao, Yuhai, et al.
Publicado: (2015)

Microbiome-Mediated Upregulation of MicroRNA-146a in Sporadic Alzheimer’s Disease
por: Zhao, Yuhai, et al.
Publicado: (2018)

Over-Expressed Pathogenic miRNAs in Alzheimer’s Disease (AD) and Prion Disease (PrD) Drive Deficits in TREM2-Mediated Aβ42 Peptide Clearance
por: Zhao, Yuhai, et al.
Publicado: (2016)

Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer’s Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7)
por: Zhao, Yuhai, et al.
Publicado: (2016)

microRNA-34a (miRNA-34a) Mediated Down-Regulation of the Post-synaptic Cytoskeletal Element SHANK3 in Sporadic Alzheimer's Disease (AD)
por: Zhao, Yuhai, et al.
Publicado: (2019)

MicroRNA (miRNA) Complexity in Alzheimer’s Disease (AD)
por: Lukiw, Walter J.
Publicado: (2023)

Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus
por: Zhao, Yuhai, et al.
Publicado: (2017)

Down-Regulation of Essential Synaptic Components by GI-Tract Microbiome-Derived Lipopolysaccharide (LPS) in LPS-Treated Human Neuronal-Glial (HNG) Cells in Primary Culture: Relevance to Alzheimer’s Disease (AD)
por: Zhao, Yuhai, et al.
Publicado: (2019)

MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer’s Disease (AD)-Novel and Unique Pathological Features
por: Zhao, Yuhai, et al.
Publicado: (2015)

NF-kB (p50/p65)-Mediated Pro-Inflammatory microRNA (miRNA) Signaling in Alzheimer's Disease (AD)
por: Lukiw, Walter J.
Publicado: (2022)

Anti-microRNAs as Novel Therapeutic Agents in the Clinical Management of Alzheimer's Disease
por: Zhao, Yuhai, et al.
Publicado: (2016)

Deficits in the miRNA-34a-regulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer's disease (AD); an update
por: Bhattacharjee, Surjyadipta, et al.
Publicado: (2014)

Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders
por: Alexandrov, Peter N., et al.
Publicado: (2017)

Variability in micro RNA (miRNA) abundance, speciation and complexity amongst different human populations and potential relevance to Alzheimer's disease (AD)
por: Lukiw, Walter J.
Publicado: (2013)

Aluminum and its potential contribution to Alzheimer's disease (AD)
por: Bhattacharjee, Surjyadipta, et al.
Publicado: (2014)

Pathogenic microbes, the microbiome, and Alzheimer’s disease (AD)
por: Hill, James M., et al.
Publicado: (2014)

microRNA-146a Signaling in Alzheimer's Disease (AD) and Prion Disease (PrD)
por: Lukiw, Walter J.
Publicado: (2020)

Lipopolysaccharide (LPS) Accumulates in Neocortical Neurons of Alzheimer’s Disease (AD) Brain and Impairs Transcription in Human Neuronal-Glial Primary Co-cultures
por: Zhao, Yuhai, et al.
Publicado: (2017)

MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints
por: Vergallo, Andrea, et al.
Publicado: (2021)

Lipopolysaccharides (LPSs) as Potent Neurotoxic Glycolipids in Alzheimer’s Disease (AD)
por: Zhao, Yuhai, et al.
Publicado: (2022)

SARS-CoV-2, long COVID, prion disease and neurodegeneration
por: Zhao, Yuhai, et al.
Publicado: (2022)

Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer’s Precision Medicine and Pharmacology
por: Hampel, Harald, et al.
Publicado: (2019)

Genetics of Aggression in Alzheimer’s Disease (AD)
por: Lukiw, Walter J., et al.
Publicado: (2017)

Microbiome-Derived Lipopolysaccharide (LPS) Selectively Inhibits Neurofilament Light Chain (NF-L) Gene Expression in Human Neuronal-Glial (HNG) Cells in Primary Culture
por: Lukiw, Walter J., et al.
Publicado: (2018)

Gastrointestinal Tract Microbiome-Derived Pro-inflammatory Neurotoxins in Alzheimer’s Disease
por: Zhao, Yuhai, et al.
Publicado: (2021)

Microbial-generated amyloids and Alzheimer's disease (AD)
por: Hill, James M., et al.
Publicado: (2015)

Microbiome-Derived Lipopolysaccharide Enriched in the Perinuclear Region of Alzheimer’s Disease Brain
por: Zhao, Yuhai, et al.
Publicado: (2017)

Alterations in micro RNA-messenger RNA (miRNA-mRNA) Coupled Signaling Networks in Sporadic Alzheimer’s Disease (AD) Hippocampal CA1
por: Jaber, V, et al.
Publicado: (2017)

Circular RNA (circRNA) in Alzheimer's disease (AD)
por: Lukiw, Walter J.
Publicado: (2013)

SARS-CoV-2 Neuroinvasion, Inflammatory Neurodegeneration and Alzheimer's Disease
por: Zhao, Yuhai, et al.
Publicado: (2022)

TREM2 signaling, miRNA-34a and the extinction of phagocytosis
por: Zhao, Yuhai, et al.
Publicado: (2013)

Pathogenic microRNAs Common to Brain and Retinal Degeneration; Recent Observations in Alzheimer’s Disease and Age-Related Macular Degeneration
por: Hill, James M., et al.
Publicado: (2015)

Treating Alzheimer’s Disease (AD) with Light and Sound
por: Lukiw, Walter J
Publicado: (2020)

Gastrointestinal (GI)-Tract Microbiome Derived Neurotoxins and their Potential Contribution to Inflammatory Neurodegeneration in Alzheimer’s Disease (AD)
por: Lukiw, Walter J., et al.
Publicado: (2021)

MicroRNA-455-3p as a Potential Biomarker for Alzheimer's Disease: An Update
por: Kumar, Subodh, et al.
Publicado: (2018)

Up-Regulation of miRNA-146a in Progressive, Age-Related Inflammatory Neurodegenerative Disorders of the Human CNS
por: Alexandrov, Peter N., et al.
Publicado: (2014)

Alzheimer's disease (AD) as a disorder of the plasma membrane
por: Lukiw, Walter J.
Publicado: (2013)

Partial Volume Correction Increases the Sensitivity of 18F-Florbetapir-Positron Emission Tomography for the Detection of Early Stage Amyloidosis
por: Teipel, Stefan J., et al.
Publicado: (2021)

Circulating microRNAs in Alzheimer’s disease: the search for novel biomarkers
por: Dorval, Véronique, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ktv64tg307h6cvsnk47rcr0it9