Cargando…

Influence of Lipoxygenase Inhibition on Glioblastoma Cell Biology

Background: The relationship between glioblastoma (GBM) and fatty acid metabolism could be the key to elucidate more effective therapeutic targets. 15-lipoxygenase-1 (15-LOX), a linolenic acid and arachidonic acid metabolizing enzyme, induces both pro- and antitumorigenic effects in different cancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Souza, Felipe da Costa, Ferreira, Matthew Thomas, Colquhoun, Alison
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664864/ https://www.ncbi.nlm.nih.gov/pubmed/33182324 http://dx.doi.org/10.3390/ijms21218395

Ejemplares similares

Cyclooxygenase Inhibition Alters Proliferative, Migratory, and Invasive Properties of Human Glioblastoma Cells In Vitro
por: Ferreira, Matthew Thomas, et al.
Publicado: (2021)

Lipoxygenase Inhibition by Plant Extracts
por: Lončarić, Melita, et al.
Publicado: (2021)

Inhibition of tumour growth by lipoxygenase inhibitors.
por: Hussey, H. J., et al.
Publicado: (1996)

Eicosanoids and cancer
por: Gomes, Renata Nascimento, et al.
Publicado: (2018)

Development of nanostructured formulation from naringenin and silk fibroin and application for inhibition of lipoxygenase (LOX)
por: Holanda, Fabrício H., et al.
Publicado: (2023)

Effect of Polyunsaturated Fatty Acids on Temozolomide Drug-Sensitive and Drug-Resistant Glioblastoma Cells
por: Silva, Janaína Alessandra, et al.
Publicado: (2023)

Inhibition of 5-Lipoxygenase in Hepatic Stellate Cells Alleviates Liver Fibrosis
por: Pu, Shiyun, et al.
Publicado: (2021)

5-Lipoxygenase Deficiency Reduces Acetaminophen-Induced Hepatotoxicity and Lethality
por: Hohmann, Miriam S. N., et al.
Publicado: (2013)

15-Lipoxygenase Metabolites of Docosahexaenoic Acid Inhibit Prostate Cancer Cell Proliferation and Survival
por: O’Flaherty, Joseph T., et al.
Publicado: (2012)

Avenanthramides as lipoxygenase inhibitors
por: Landberg, Rikard, et al.
Publicado: (2020)

5-Lipoxygenase Inhibition of the Fructus of Foeniculum vulgare and Its Constituents
por: Lee, Je Hyeong, et al.
Publicado: (2012)

Inhibition of 5-lipoxygenase alleviates graft-versus-host disease
por: Rezende, Barbara Maximino, et al.
Publicado: (2017)

Convergence of eicosanoid and integrin biology: 12-lipoxygenase seeks a partner
por: Tang, Keqin, et al.
Publicado: (2015)

Lipoxygenases—Killers against Their Will?
por: Friedmann Angeli, José Pedro, et al.
Publicado: (2018)

12/15-lipoxygenase inhibition attenuates neuroinflammation by suppressing inflammasomes
por: Cakir-Aktas, Canan, et al.
Publicado: (2023)

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids
por: Gheorghe, Karina Roxana, et al.
Publicado: (2009)

Lipoxygenase Inhibition Activity of Coumarin Derivatives—QSAR and Molecular Docking Study
por: Lončarić, Melita, et al.
Publicado: (2020)

Inhibition of 5-Lipoxygenase Pathway Attenuates Acute Liver Failure by Inhibiting Macrophage Activation
por: Li, Lu, et al.
Publicado: (2014)

5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes
Publicado: (1993)

Inhibition of Soybean 15-Lipoxygenase and Human 5-Lipoxygenase by Extracts of Leaves, Stem Bark, Phenols and Catechols Isolated From Lithraea caustica (Anacardiaceae)
por: Muñoz-Ramírez, Alejandra, et al.
Publicado: (2020)

Systemic inhibition of 5-lipoxygenase by MK-886 exacerbates apical periodontitis bone loss in a mouse model
por: Petean, Igor Bassi Ferreira, et al.
Publicado: (2023)

Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction
por: Abueid, Leyla, et al.
Publicado: (2017)

Inhibition of Lipoxygenases Showed No Benefit for the Musculoskeletal System in Estrogen Deficient Rats
por: Saul, Dominik, et al.
Publicado: (2021)

Paeonol prevents migration and invasion, and promotes apoptosis of cervical cancer cells by inhibiting 5-lipoxygenase
por: Sheng, Shao-Qin, et al.
Publicado: (2021)

Discovery of α-Linolenic Acid 16(S)-Lipoxygenase: Cucumber (Cucumis sativus L.) Vegetative Lipoxygenase 3
por: Gorina, Svetlana S., et al.
Publicado: (2023)

Recombinant Soybean Lipoxygenase 2 (GmLOX2) Acts Primarily as a ω6(S)-Lipoxygenase
por: Smirnova, Elena O., et al.
Publicado: (2023)

5-Lipoxygenase Pathway, Dendritic Cells, and Adaptive Immunity
por: Hedi, Harizi, et al.
Publicado: (2004)

Phthalimide analogs as probable 15-lipoxygenase-1 inhibitors: synthesis, biological evaluation and docking studies
por: Aliabadi, Alireza, et al.
Publicado: (2015)

Local inhibition of 5-lipoxygenase enhances bone formation in a rat model
por: Cottrell, J. A., et al.
Publicado: (2013)

Ambient fine particulate matter inhibits 15-lipoxygenases to promote lung carcinogenesis
por: Li, Ming-Yue, et al.
Publicado: (2019)

Functional characterization of genetic enzyme variations in human lipoxygenases()
por: Horn, Thomas, et al.
Publicado: (2013)

The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells
por: Zappavigna, S., et al.
Publicado: (2016)

Hydrogen Tunneling in a Prokaryotic Lipoxygenase
por: Carr, Cody A. Marcus, et al.
Publicado: (2014)

The Lipoxygenases: Their Regulation and Implication in Alzheimer’s Disease
por: Czapski, Grzegorz A., et al.
Publicado: (2015)

Regulation of Tissue Inflammation by 12-Lipoxygenases
por: Kulkarni, Abhishek, et al.
Publicado: (2021)

A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells
Publicado: (1992)

Arachidonic acid promotes the binding of 5-lipoxygenase on nanodiscs containing 5-lipoxygenase activating protein in the absence of calcium-ions
por: Kumar, Ramakrishnan B., et al.
Publicado: (2020)

Methods for identifying lipoxygenase producing microorganisms on agar plates
por: Nyyssölä, Antti, et al.
Publicado: (2012)

Emerging Roles of 5-Lipoxygenase Phosphorylation in Inflammation and Cell Death
por: Sun, Qian-Yi, et al.
Publicado: (2019)

Cyclooxygenase/lipoxygenase shunting lowers the anti-cancer effect of cyclooxygenase-2 inhibition in colorectal cancer cells
por: Ganesh, Radhakrishnan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ciu3p2a18sma0broiuoqkv9gi7