Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease

The aim of the study was to report quetiapine-relieved Pisa syndrome in a patient with Parkinson disease and to discuss the pathogenesis and treatment of Pisa syndrome. METHODS: We report a 74-year-old female patient with a history of Parkinson disease for 7 years. Pisa syndrome, lateral deviation o...

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Detalles Bibliográficos
Autores principales: Zhao, Junwu, Wang, Quan, Sun, Hairong, Liu, Xiaoxiao, Leng, Bing, Wang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664973/
https://www.ncbi.nlm.nih.gov/pubmed/32991348
http://dx.doi.org/10.1097/WNF.0000000000000416
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author Zhao, Junwu
Wang, Quan
Sun, Hairong
Liu, Xiaoxiao
Leng, Bing
Wang, Tong
author_facet Zhao, Junwu
Wang, Quan
Sun, Hairong
Liu, Xiaoxiao
Leng, Bing
Wang, Tong
author_sort Zhao, Junwu
collection PubMed
description The aim of the study was to report quetiapine-relieved Pisa syndrome in a patient with Parkinson disease and to discuss the pathogenesis and treatment of Pisa syndrome. METHODS: We report a 74-year-old female patient with a history of Parkinson disease for 7 years. Pisa syndrome, lateral deviation of the spine and leaning to one side, appeared more than a year ago; adjusting levodopa was ineffective. After treatment with quetiapine for visual hallucinations, the patient's right side tilt was completely relieved after taking the drug for 1 month. CONCLUSIONS: Drug-related Pisa syndrome may be associated with the imbalance in dopamine-choline. Pisa syndrome may have similar mechanisms and treatment options to dystonia. This is the first report of quetiapine relieving Pisa syndrome in a patient with Parkinson disease.
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spelling pubmed-76649732020-11-16 Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease Zhao, Junwu Wang, Quan Sun, Hairong Liu, Xiaoxiao Leng, Bing Wang, Tong Clin Neuropharmacol Original Articles The aim of the study was to report quetiapine-relieved Pisa syndrome in a patient with Parkinson disease and to discuss the pathogenesis and treatment of Pisa syndrome. METHODS: We report a 74-year-old female patient with a history of Parkinson disease for 7 years. Pisa syndrome, lateral deviation of the spine and leaning to one side, appeared more than a year ago; adjusting levodopa was ineffective. After treatment with quetiapine for visual hallucinations, the patient's right side tilt was completely relieved after taking the drug for 1 month. CONCLUSIONS: Drug-related Pisa syndrome may be associated with the imbalance in dopamine-choline. Pisa syndrome may have similar mechanisms and treatment options to dystonia. This is the first report of quetiapine relieving Pisa syndrome in a patient with Parkinson disease. Lippincott Williams & Wilkins 2020 2020-09-28 /pmc/articles/PMC7664973/ /pubmed/32991348 http://dx.doi.org/10.1097/WNF.0000000000000416 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Original Articles
Zhao, Junwu
Wang, Quan
Sun, Hairong
Liu, Xiaoxiao
Leng, Bing
Wang, Tong
Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease
title Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease
title_full Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease
title_fullStr Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease
title_full_unstemmed Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease
title_short Quetiapine Relieved Pisa Syndrome in Patient With Parkinson Disease
title_sort quetiapine relieved pisa syndrome in patient with parkinson disease
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664973/
https://www.ncbi.nlm.nih.gov/pubmed/32991348
http://dx.doi.org/10.1097/WNF.0000000000000416
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