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Identification of a nuclear localization signal in the Plasmodium falciparum CTP: phosphocholine cytidylyltransferase enzyme

The phospholipid biosynthesis of the malaria parasite, Plasmodium falciparum is a key process for its survival and its inhibition is a validated antimalarial therapeutic approach. The second and rate-limiting step of the de novo phosphatidylcholine biosynthesis is catalysed by CTP: phosphocholine cy...

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Detalles Bibliográficos
Autores principales: Izrael, Richard, Marton, Lívia, Nagy, Gergely N., Pálinkás, Hajnalka L., Kucsma, Nóra, Vértessy, Beáta G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665022/
https://www.ncbi.nlm.nih.gov/pubmed/33184408
http://dx.doi.org/10.1038/s41598-020-76829-1