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Identification of a nuclear localization signal in the Plasmodium falciparum CTP: phosphocholine cytidylyltransferase enzyme
The phospholipid biosynthesis of the malaria parasite, Plasmodium falciparum is a key process for its survival and its inhibition is a validated antimalarial therapeutic approach. The second and rate-limiting step of the de novo phosphatidylcholine biosynthesis is catalysed by CTP: phosphocholine cy...
Autores principales: | Izrael, Richard, Marton, Lívia, Nagy, Gergely N., Pálinkás, Hajnalka L., Kucsma, Nóra, Vértessy, Beáta G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665022/ https://www.ncbi.nlm.nih.gov/pubmed/33184408 http://dx.doi.org/10.1038/s41598-020-76829-1 |
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