Cargando…

Association of Cotinine-Verified Cigarette Exposure with Chronic Rhinosinusitis in Korean Adults

Chronic rhinosinusitis is known to be influenced by cigarette exposure; however, this relationship is based on the presence of nasal polyps, and objective measurements of cigarette exposure in chronic rhinosinusitis are not well established. This study aimed to estimate the association between chron...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Kijeong, Choi, In Hak, Lee, Hoyoung, Choi, Soojeong, Lee, Sang Hag, Kim, Tae Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665152/
https://www.ncbi.nlm.nih.gov/pubmed/33182521
http://dx.doi.org/10.3390/ijerph17218291
_version_ 1783609963951685632
author Lee, Kijeong
Choi, In Hak
Lee, Hoyoung
Choi, Soojeong
Lee, Sang Hag
Kim, Tae Hoon
author_facet Lee, Kijeong
Choi, In Hak
Lee, Hoyoung
Choi, Soojeong
Lee, Sang Hag
Kim, Tae Hoon
author_sort Lee, Kijeong
collection PubMed
description Chronic rhinosinusitis is known to be influenced by cigarette exposure; however, this relationship is based on the presence of nasal polyps, and objective measurements of cigarette exposure in chronic rhinosinusitis are not well established. This study aimed to estimate the association between chronic rhinosinusitis and smoking status based on self-reported questionnaires and urinary cotinine levels according to the presence of nasal polyps. We analyzed a total of 23,621 participants who participated from the fifth Korea National Health and Nutrition Examination Survey (2010–2012). Serum total and specific IgE level were measured. Higher prevalence of chronic rhinosinusitis with nasal polyps was associated with current smoking status (OR = 1.43, 95% CI = 1.00–2.03). This association was prevalent in participants aged ≤ 50 years (OR = 1.76, 95% CI = 1.01–3.05), and higher urinary cotinine level showed correlation with higher prevalence of chronic rhinosinusitis with nasal polyps in this age group (OR = 1.04, 95% CI = 1.00–1.08). In addition, positive correlation between serum total IgE and urinary cotinine levels was greater in patients with chronic rhinosinusitis (β = 0.493, 95% CI = 0.071–0.916) than in controls (β = 0.062, 95% CI = 0.021–0.103). Aggressive smoking interventions should be performed in patients with chronic rhinosinusitis with nasal polyp, especially in cases of young adults or high serum IgE levels.
format Online
Article
Text
id pubmed-7665152
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-76651522020-11-14 Association of Cotinine-Verified Cigarette Exposure with Chronic Rhinosinusitis in Korean Adults Lee, Kijeong Choi, In Hak Lee, Hoyoung Choi, Soojeong Lee, Sang Hag Kim, Tae Hoon Int J Environ Res Public Health Article Chronic rhinosinusitis is known to be influenced by cigarette exposure; however, this relationship is based on the presence of nasal polyps, and objective measurements of cigarette exposure in chronic rhinosinusitis are not well established. This study aimed to estimate the association between chronic rhinosinusitis and smoking status based on self-reported questionnaires and urinary cotinine levels according to the presence of nasal polyps. We analyzed a total of 23,621 participants who participated from the fifth Korea National Health and Nutrition Examination Survey (2010–2012). Serum total and specific IgE level were measured. Higher prevalence of chronic rhinosinusitis with nasal polyps was associated with current smoking status (OR = 1.43, 95% CI = 1.00–2.03). This association was prevalent in participants aged ≤ 50 years (OR = 1.76, 95% CI = 1.01–3.05), and higher urinary cotinine level showed correlation with higher prevalence of chronic rhinosinusitis with nasal polyps in this age group (OR = 1.04, 95% CI = 1.00–1.08). In addition, positive correlation between serum total IgE and urinary cotinine levels was greater in patients with chronic rhinosinusitis (β = 0.493, 95% CI = 0.071–0.916) than in controls (β = 0.062, 95% CI = 0.021–0.103). Aggressive smoking interventions should be performed in patients with chronic rhinosinusitis with nasal polyp, especially in cases of young adults or high serum IgE levels. MDPI 2020-11-09 2020-11 /pmc/articles/PMC7665152/ /pubmed/33182521 http://dx.doi.org/10.3390/ijerph17218291 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Kijeong
Choi, In Hak
Lee, Hoyoung
Choi, Soojeong
Lee, Sang Hag
Kim, Tae Hoon
Association of Cotinine-Verified Cigarette Exposure with Chronic Rhinosinusitis in Korean Adults
title Association of Cotinine-Verified Cigarette Exposure with Chronic Rhinosinusitis in Korean Adults
title_full Association of Cotinine-Verified Cigarette Exposure with Chronic Rhinosinusitis in Korean Adults
title_fullStr Association of Cotinine-Verified Cigarette Exposure with Chronic Rhinosinusitis in Korean Adults
title_full_unstemmed Association of Cotinine-Verified Cigarette Exposure with Chronic Rhinosinusitis in Korean Adults
title_short Association of Cotinine-Verified Cigarette Exposure with Chronic Rhinosinusitis in Korean Adults
title_sort association of cotinine-verified cigarette exposure with chronic rhinosinusitis in korean adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665152/
https://www.ncbi.nlm.nih.gov/pubmed/33182521
http://dx.doi.org/10.3390/ijerph17218291
work_keys_str_mv AT leekijeong associationofcotinineverifiedcigaretteexposurewithchronicrhinosinusitisinkoreanadults
AT choiinhak associationofcotinineverifiedcigaretteexposurewithchronicrhinosinusitisinkoreanadults
AT leehoyoung associationofcotinineverifiedcigaretteexposurewithchronicrhinosinusitisinkoreanadults
AT choisoojeong associationofcotinineverifiedcigaretteexposurewithchronicrhinosinusitisinkoreanadults
AT leesanghag associationofcotinineverifiedcigaretteexposurewithchronicrhinosinusitisinkoreanadults
AT kimtaehoon associationofcotinineverifiedcigaretteexposurewithchronicrhinosinusitisinkoreanadults