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Withaferin A activates TRIM16 for its anti-cancer activity in melanoma
Although selective BRAF inhibitors and novel immunotherapies have improved short-term treatment responses in metastatic melanoma patients, acquired resistance to these therapeutics still represent a major challenge in clinical practice. In this study, we evaluated the efficacy of Withaferin A (WFA),...
Autores principales: | Nagy, Zsuzsanna, Cheung, Belamy B., Tsang, Wing, Tan, Owen, Herath, Mika, Ciampa, Olivia C., Shadma, Fatima, Carter, Daniel R., Marshall, Glenn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665169/ https://www.ncbi.nlm.nih.gov/pubmed/33184347 http://dx.doi.org/10.1038/s41598-020-76722-x |
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