Induction of NEDD8-conjugating enzyme E2 UBE2F by platinum protects lung cancer cells from apoptosis and confers to platinum-insensitivity

Platinum is a widely used first-line chemotherapy in treating non-small cell lung cancer of adenocarcinoma. Unfortunately, platinum resistance leads to relapse and therapeutic failure, enabling the development of platinum-sensitization strategies to be of great clinical significance. Here, we report...

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Detalles Bibliográficos
Autores principales: Zhou, Lisha, Zhu, Jin, Chen, Wangyang, Jiang, Yanyu, Hu, Tao, Wang, Yinxia, Ye, Xiaoling, Zhan, Mengxi, Ji, Chenghao, Xu, Zhuoming, Wang, Xinran, Gu, Yuanlong, Jia, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665193/
https://www.ncbi.nlm.nih.gov/pubmed/33184273
http://dx.doi.org/10.1038/s41419-020-03184-4

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