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Low Level Donor Chimerism of CD19 CAR-T Cells Returned to Complete Donor Chimerism in Patients with Relapse After Allo-Hematopoietic Stem Cell Transplant

PURPOSE: To investigate the donor chimerism changes and curative effects associated with the use of autologous anti-CD19 chimeric antigen receptor (CAR) T cells with B-cell acute lymphoblastic leukemia (B-ALL) presenting with a low donor chimerism level and relapse after allogeneic hematopoietic ste...

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Detalles Bibliográficos
Autores principales: Li, Qing, Mu, Juan, Yuan, Jijun, Yang, Zhenxing, Wang, Jia, Deng, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665456/
https://www.ncbi.nlm.nih.gov/pubmed/33204102
http://dx.doi.org/10.2147/OTT.S277146