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A forum on synthetic biology: meet the great challenges with new technology
Synthetic biology aims to redesign and reconstruct living systems for understanding life or for useful real-world applications. In the past two decades, scientists have been able to use engineered living systems to produce many kinds of products from bioplastics to drugs, to construct a minimal bact...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665648/ https://www.ncbi.nlm.nih.gov/pubmed/34676090 http://dx.doi.org/10.1093/nsr/nwaa252 |
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author | Zhao, Weijie |
author_facet | Zhao, Weijie |
author_sort | Zhao, Weijie |
collection | PubMed |
description | Synthetic biology aims to redesign and reconstruct living systems for understanding life or for useful real-world applications. In the past two decades, scientists have been able to use engineered living systems to produce many kinds of products from bioplastics to drugs, to construct a minimal bacterium with a fully synthetic genome and to store huge amount of information within a cell. And in 2020, when the COVID-19 pandemic swept across the world, the synthetic biology community became one of the major forces to develop effective diagnostic approaches as well as the drugs and vaccines, to rapidly cope with this great challenge with the state-of-the-art technologies in their hands. In this panel discussion held on 3rd August 2020, eleven pioneering synthetic biologists from six countries across four continents gathered to discuss the development trend, challenges and biosafety issues concerning synthetic biology. [Image: see text] George Church Professor of Genetics at Harvard Medical School and Professor of Health Sciences and Technology at Harvard and MIT, USA [Image: see text] Paul Freemont Professor of Structural Biology in the Department of Infectious Disease at Imperial College and a member of the Science Advisory Board of Tierra Biosciences, UK [Image: see text] Akihiko Kondo Professor in School of Science, Technology and Innovation, and Department of Chemical Science and Engineering at Kobe University, Japan [Image: see text] Christina Smolke Professor of Bioengineering and of Chemical Engineering at Stanford University and CEO of Antheia Inc., USA [Image: see text] Xian-En Zhang Professor at the Institute of Biophysics, Chinese Academy of Sciences, China [Image: see text] Chenli Liu (Chair) Professor and Director of Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China [Image: see text] Jim Collins Termeer Professor of Medical Engineering & Science and Professor of Biological Engineering at MIT, USA [Image: see text] Jay Keasling Professor of Chemical Engineering and Bioengineering at the University of California, Berkeley, USA [Image: see text] Sang Yup Lee Dean of KAIST Institutes and Distinguished Professor in the Department of Chemical and Biomolecular Engineering at Korea Advanced Institute of Science and Technology (KAIST), South Korea [Image: see text] Claudia Vickers Director of the Future Science Platform in Synthetic Biology at Commonwealth Science and Industry Research Organization (CSIRO), Australia [Image: see text] Guoping Zhao Professor at the Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China |
format | Online Article Text |
id | pubmed-7665648 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-76656482020-11-16 A forum on synthetic biology: meet the great challenges with new technology Zhao, Weijie Natl Sci Rev Forum Synthetic biology aims to redesign and reconstruct living systems for understanding life or for useful real-world applications. In the past two decades, scientists have been able to use engineered living systems to produce many kinds of products from bioplastics to drugs, to construct a minimal bacterium with a fully synthetic genome and to store huge amount of information within a cell. And in 2020, when the COVID-19 pandemic swept across the world, the synthetic biology community became one of the major forces to develop effective diagnostic approaches as well as the drugs and vaccines, to rapidly cope with this great challenge with the state-of-the-art technologies in their hands. In this panel discussion held on 3rd August 2020, eleven pioneering synthetic biologists from six countries across four continents gathered to discuss the development trend, challenges and biosafety issues concerning synthetic biology. [Image: see text] George Church Professor of Genetics at Harvard Medical School and Professor of Health Sciences and Technology at Harvard and MIT, USA [Image: see text] Paul Freemont Professor of Structural Biology in the Department of Infectious Disease at Imperial College and a member of the Science Advisory Board of Tierra Biosciences, UK [Image: see text] Akihiko Kondo Professor in School of Science, Technology and Innovation, and Department of Chemical Science and Engineering at Kobe University, Japan [Image: see text] Christina Smolke Professor of Bioengineering and of Chemical Engineering at Stanford University and CEO of Antheia Inc., USA [Image: see text] Xian-En Zhang Professor at the Institute of Biophysics, Chinese Academy of Sciences, China [Image: see text] Chenli Liu (Chair) Professor and Director of Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China [Image: see text] Jim Collins Termeer Professor of Medical Engineering & Science and Professor of Biological Engineering at MIT, USA [Image: see text] Jay Keasling Professor of Chemical Engineering and Bioengineering at the University of California, Berkeley, USA [Image: see text] Sang Yup Lee Dean of KAIST Institutes and Distinguished Professor in the Department of Chemical and Biomolecular Engineering at Korea Advanced Institute of Science and Technology (KAIST), South Korea [Image: see text] Claudia Vickers Director of the Future Science Platform in Synthetic Biology at Commonwealth Science and Industry Research Organization (CSIRO), Australia [Image: see text] Guoping Zhao Professor at the Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China Oxford University Press 2020-10-17 /pmc/articles/PMC7665648/ /pubmed/34676090 http://dx.doi.org/10.1093/nsr/nwaa252 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Forum Zhao, Weijie A forum on synthetic biology: meet the great challenges with new technology |
title | A forum on synthetic biology: meet the great challenges with new technology |
title_full | A forum on synthetic biology: meet the great challenges with new technology |
title_fullStr | A forum on synthetic biology: meet the great challenges with new technology |
title_full_unstemmed | A forum on synthetic biology: meet the great challenges with new technology |
title_short | A forum on synthetic biology: meet the great challenges with new technology |
title_sort | forum on synthetic biology: meet the great challenges with new technology |
topic | Forum |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665648/ https://www.ncbi.nlm.nih.gov/pubmed/34676090 http://dx.doi.org/10.1093/nsr/nwaa252 |
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