Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19

This study evaluates the predictive value of circulating inflammatory markers, especially neopterin, in patients with coronavirus disease 2019 (COVID-19). Within this retrospective analysis of 115 hospitalized COVID-19 patients, elevated neopterin levels upon admission were significantly associated...

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Detalles Bibliográficos
Autores principales: Bellmann-Weiler, Rosa, Lanser, Lukas, Burkert, Francesco, Seiwald, Stefanie, Fritsche, Gernot, Wildner, Sophie, Schroll, Andrea, Koppelstätter, Sabine, Kurz, Katharina, Griesmacher, Andrea, Weiss, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665702/
https://www.ncbi.nlm.nih.gov/pubmed/33442554
http://dx.doi.org/10.1093/ofid/ofaa521
Descripción
Sumario:This study evaluates the predictive value of circulating inflammatory markers, especially neopterin, in patients with coronavirus disease 2019 (COVID-19). Within this retrospective analysis of 115 hospitalized COVID-19 patients, elevated neopterin levels upon admission were significantly associated with disease severity, risk for intensive care unit admission, need for mechanical ventilation, and death. Therefore, neopterin is a reliable predictive marker in patients with COVID-19 and may help to improve the clinical management of patients.

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