Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19

This study evaluates the predictive value of circulating inflammatory markers, especially neopterin, in patients with coronavirus disease 2019 (COVID-19). Within this retrospective analysis of 115 hospitalized COVID-19 patients, elevated neopterin levels upon admission were significantly associated...

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Autores principales: Bellmann-Weiler, Rosa, Lanser, Lukas, Burkert, Francesco, Seiwald, Stefanie, Fritsche, Gernot, Wildner, Sophie, Schroll, Andrea, Koppelstätter, Sabine, Kurz, Katharina, Griesmacher, Andrea, Weiss, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665702/
https://www.ncbi.nlm.nih.gov/pubmed/33442554
http://dx.doi.org/10.1093/ofid/ofaa521
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author Bellmann-Weiler, Rosa
Lanser, Lukas
Burkert, Francesco
Seiwald, Stefanie
Fritsche, Gernot
Wildner, Sophie
Schroll, Andrea
Koppelstätter, Sabine
Kurz, Katharina
Griesmacher, Andrea
Weiss, Günter
author_facet Bellmann-Weiler, Rosa
Lanser, Lukas
Burkert, Francesco
Seiwald, Stefanie
Fritsche, Gernot
Wildner, Sophie
Schroll, Andrea
Koppelstätter, Sabine
Kurz, Katharina
Griesmacher, Andrea
Weiss, Günter
author_sort Bellmann-Weiler, Rosa
collection PubMed
description This study evaluates the predictive value of circulating inflammatory markers, especially neopterin, in patients with coronavirus disease 2019 (COVID-19). Within this retrospective analysis of 115 hospitalized COVID-19 patients, elevated neopterin levels upon admission were significantly associated with disease severity, risk for intensive care unit admission, need for mechanical ventilation, and death. Therefore, neopterin is a reliable predictive marker in patients with COVID-19 and may help to improve the clinical management of patients.
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spelling pubmed-76657022020-11-16 Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19 Bellmann-Weiler, Rosa Lanser, Lukas Burkert, Francesco Seiwald, Stefanie Fritsche, Gernot Wildner, Sophie Schroll, Andrea Koppelstätter, Sabine Kurz, Katharina Griesmacher, Andrea Weiss, Günter Open Forum Infect Dis Brief Reports This study evaluates the predictive value of circulating inflammatory markers, especially neopterin, in patients with coronavirus disease 2019 (COVID-19). Within this retrospective analysis of 115 hospitalized COVID-19 patients, elevated neopterin levels upon admission were significantly associated with disease severity, risk for intensive care unit admission, need for mechanical ventilation, and death. Therefore, neopterin is a reliable predictive marker in patients with COVID-19 and may help to improve the clinical management of patients. Oxford University Press 2020-11-03 /pmc/articles/PMC7665702/ /pubmed/33442554 http://dx.doi.org/10.1093/ofid/ofaa521 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Bellmann-Weiler, Rosa
Lanser, Lukas
Burkert, Francesco
Seiwald, Stefanie
Fritsche, Gernot
Wildner, Sophie
Schroll, Andrea
Koppelstätter, Sabine
Kurz, Katharina
Griesmacher, Andrea
Weiss, Günter
Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19
title Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19
title_full Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19
title_fullStr Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19
title_full_unstemmed Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19
title_short Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19
title_sort neopterin predicts disease severity in hospitalized patients with covid-19
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665702/
https://www.ncbi.nlm.nih.gov/pubmed/33442554
http://dx.doi.org/10.1093/ofid/ofaa521
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