Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study

This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clin...

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Detalles Bibliográficos
Autores principales: Ooi, Say Tat, Parthasarathy, Purnima, Lin, Yi, Nallakaruppan, Valliammai D/O, Ng, Shereen, Tan, Teck Choon, Low, Serena, Tang, Terence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665708/
https://www.ncbi.nlm.nih.gov/pubmed/33235888
http://dx.doi.org/10.1093/ofid/ofaa486
Descripción
Sumario:This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia.

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