Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study

This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ooi, Say Tat, Parthasarathy, Purnima, Lin, Yi, Nallakaruppan, Valliammai D/O, Ng, Shereen, Tan, Teck Choon, Low, Serena, Tang, Terence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665708/
https://www.ncbi.nlm.nih.gov/pubmed/33235888
http://dx.doi.org/10.1093/ofid/ofaa486
_version_ 1783610023769800704
author Ooi, Say Tat
Parthasarathy, Purnima
Lin, Yi
Nallakaruppan, Valliammai D/O
Ng, Shereen
Tan, Teck Choon
Low, Serena
Tang, Terence
author_facet Ooi, Say Tat
Parthasarathy, Purnima
Lin, Yi
Nallakaruppan, Valliammai D/O
Ng, Shereen
Tan, Teck Choon
Low, Serena
Tang, Terence
author_sort Ooi, Say Tat
collection PubMed
description This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia.
format Online
Article
Text
id pubmed-7665708
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-76657082020-11-16 Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study Ooi, Say Tat Parthasarathy, Purnima Lin, Yi Nallakaruppan, Valliammai D/O Ng, Shereen Tan, Teck Choon Low, Serena Tang, Terence Open Forum Infect Dis Brief Reports This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia. Oxford University Press 2020-10-14 /pmc/articles/PMC7665708/ /pubmed/33235888 http://dx.doi.org/10.1093/ofid/ofaa486 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Ooi, Say Tat
Parthasarathy, Purnima
Lin, Yi
Nallakaruppan, Valliammai D/O
Ng, Shereen
Tan, Teck Choon
Low, Serena
Tang, Terence
Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
title Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
title_full Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
title_fullStr Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
title_full_unstemmed Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
title_short Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
title_sort antivirals with adjunctive corticosteroids prevent clinical progression of early coronavirus 2019 pneumonia: a retrospective cohort study
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665708/
https://www.ncbi.nlm.nih.gov/pubmed/33235888
http://dx.doi.org/10.1093/ofid/ofaa486
work_keys_str_mv AT ooisaytat antiviralswithadjunctivecorticosteroidspreventclinicalprogressionofearlycoronavirus2019pneumoniaaretrospectivecohortstudy
AT parthasarathypurnima antiviralswithadjunctivecorticosteroidspreventclinicalprogressionofearlycoronavirus2019pneumoniaaretrospectivecohortstudy
AT linyi antiviralswithadjunctivecorticosteroidspreventclinicalprogressionofearlycoronavirus2019pneumoniaaretrospectivecohortstudy
AT nallakaruppanvalliammaido antiviralswithadjunctivecorticosteroidspreventclinicalprogressionofearlycoronavirus2019pneumoniaaretrospectivecohortstudy
AT ngshereen antiviralswithadjunctivecorticosteroidspreventclinicalprogressionofearlycoronavirus2019pneumoniaaretrospectivecohortstudy
AT tanteckchoon antiviralswithadjunctivecorticosteroidspreventclinicalprogressionofearlycoronavirus2019pneumoniaaretrospectivecohortstudy
AT lowserena antiviralswithadjunctivecorticosteroidspreventclinicalprogressionofearlycoronavirus2019pneumoniaaretrospectivecohortstudy
AT tangterence antiviralswithadjunctivecorticosteroidspreventclinicalprogressionofearlycoronavirus2019pneumoniaaretrospectivecohortstudy

Ejemplares similares