Cargando…

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses

Recent outbreaks of Ebola virus (EBOV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed our limited therapeutic options for such diseases and our poor understanding of the cellular mechanisms that block viral infections. Using a transposon-mediated gene-activation screen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bruchez, Anna, Sha, Ky, Johnson, Joshua, Chen, Li, Stefani, Caroline, McConnell, Hannah, Gaucherand, Lea, Prins, Rachel, Matreyek, Kenneth A., Hume, Adam J., Mühlberger, Elke, Schmidt, Emmett V., Olinger, Gene G., Stuart, Lynda M., Lacy-Hulbert, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665841/ https://www.ncbi.nlm.nih.gov/pubmed/32855215 http://dx.doi.org/10.1126/science.abb3753

Ejemplares similares

Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III
por: Beaulieu, Yves B., et al.
Publicado: (2016)

Protective anti-tumor vaccination against glioblastoma expressing the MHC class II transactivator CIITA
por: Celesti, Fabrizio, et al.
Publicado: (2023)

The MHC-II transactivator CIITA inhibits Tat function and HIV-1 replication in human myeloid cells
por: Forlani, Greta, et al.
Publicado: (2016)

Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach
por: Wong, Daniel, et al.
Publicado: (2014)

The MHC Class II transactivator CIITA inhibits the persistent activation of NF-kB by Tax-1
por: Forlani, Greta, et al.
Publicado: (2015)

The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins
por: León Machado, Jorge Alfonso, et al.
Publicado: (2021)

The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T-Cell Lymphotropic Virus Type 1
por: Tosi, Giovanna, et al.
Publicado: (2011)

The MHC Class II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation
por: Abdallah, Rawan, et al.
Publicado: (2014)

MHC class II transactivator CIITA inhibits Tax-2-mediated HTLV-2 LTR transactivation and viral replication by binding to, and affecting Tax-2 intracellular localization
por: Orlandi, Chiara, et al.
Publicado: (2011)

CIITA and Its Dual Roles in MHC Gene Transcription
por: Devaiah, Ballachanda N., et al.
Publicado: (2013)

Labeling Ebola Virus with a Self-Splicing Fluorescent Reporter
por: Heiden, Baylee, et al.
Publicado: (2022)

The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators
por: Forlani, Greta, et al.
Publicado: (2013)

SIRT1 links CIITA deacetylation to MHC II activation
por: Wu, Xiaoyan, et al.
Publicado: (2011)

Interaction Analysis between HLA-DRB1 Shared Epitope Alleles and MHC Class II Transactivator CIITA Gene with Regard to Risk of Rheumatoid Arthritis
por: Ronninger, Marcus, et al.
Publicado: (2012)

Maturation of Dendritic Cells Is Accompanied by Rapid Transcriptional Silencing of Class II Transactivator (Ciita) Expression
por: Landmann, Salomé, et al.
Publicado: (2001)

Class II Transactivator (CIITA) Enhances Cytoplasmic Processing of HIV-1 Pr55Gag
por: Porter, Kristen A., et al.
Publicado: (2010)

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes
Publicado: (1994)

NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity
por: Santharam, Madanraj Appiya, et al.
Publicado: (2023)

Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA
Publicado: (1994)

Dysregulated Recruitment of the Histone Methyltransferase EZH2 to the Class II Transactivator (CIITA) Promoter IV in Breast Cancer Cells
por: Truax, Agnieszka D., et al.
Publicado: (2012)

IRF-4-Mediated CIITA Transcription Is Blocked by KSHV Encoded LANA to Inhibit MHC II Presentation
por: Cai, Qiliang, et al.
Publicado: (2013)

Role of PU.1 in MHC Class II Expression via CIITA Transcription in Plasmacytoid Dendritic Cells
por: Miura, Ryosuke, et al.
Publicado: (2016)

Protein arginine methyltransferase 1 (PRMT1) represses MHC II transcription in macrophages by methylating CIITA
por: Fan, Zhiwen, et al.
Publicado: (2017)

Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication
por: Orlandi, Chiara, et al.
Publicado: (2011)

Class II transactivator (CIITA) mediates transcriptional repression of pdk4 gene by interacting with hypermethylated in cancer 1 (HIC1)
por: Fang, Mingming, et al.
Publicado: (2015)

Establishment of an Inactivation Method for Ebola Virus and SARS-CoV-2 Suitable for Downstream Sequencing of Low Cell Numbers
por: Olejnik, Judith, et al.
Publicado: (2023)

GOP-1: Helping phagosomes pass the acid test
por: Stuart, Lynda M., et al.
Publicado: (2017)

Battle at the entrance gate: CIITA as a weapon to prevent the internalization of SARS-CoV-2 and Ebola viruses
por: Butowt, Rafal, et al.
Publicado: (2020)

CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments
por: Zinzow-Kramer, Wendy M., et al.
Publicado: (2012)

Toll-like receptor 4 in acute viral infection: Too much of a good thing
por: Olejnik, Judith, et al.
Publicado: (2018)

Recent advances in marburgvirus research
por: Olejnik, Judith, et al.
Publicado: (2019)

Lack of Effect of Lamivudine on Ebola Virus Replication
por: Hensley, Lisa E., et al.
Publicado: (2015)

Fowlpoxvirus recombinants coding for the CIITA gene increase the expression of endogenous MHC-II and Fowlpox Gag/Pro and Env SIV transgenes
por: Bissa, Massimiliano, et al.
Publicado: (2018)

FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA
por: Kasuga, Yusuke, et al.
Publicado: (2023)

The class II transactivator (CIITA) is regulated by post-translational modification cross-talk between ERK1/2 phosphorylation, mono-ubiquitination and Lys(63) ubiquitination
por: Morgan, Julie E., et al.
Publicado: (2015)

Interferon Regulatory Factors 1 and 2 Play Different Roles in MHC II Expression Mediated by CIITA in Grass Carp, Ctenopharyngodon idella
por: Lu, Xiao-Bing, et al.
Publicado: (2019)

Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA (Mhc2ta)
por: Hochmeister, Sonja, et al.
Publicado: (2020)

Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours
por: Ong, Chrissie E. B., et al.
Publicado: (2022)

Forty-Five Years of Marburg Virus Research
por: Brauburger, Kristina, et al.
Publicado: (2012)

Roles for common MLL/COMPASS subunits and the 19S proteasome in regulating CIITA pIV and MHC class II gene expression and promoter methylation
por: Koues, Olivia I, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ig9a3ekkjevi2k34u855fv9psd