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Reprogramming of bone marrow myeloid progenitor cells in patients with severe coronary artery disease

Atherosclerosis is the major cause of cardiovascular disease (CVD). Monocyte-derived macrophages are the most abundant immune cells in atherosclerotic plaques. In patients with atherosclerotic CVD, leukocytes have a hyperinflammatory phenotype. We hypothesize that immune cell reprogramming in these...

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Detalles Bibliográficos
Autores principales:	Noz, Marlies P, Bekkering, Siroon, Groh, Laszlo, Nielen, Tim MJ, Lamfers, Evert JP, Schlitzer, Andreas, El Messaoudi, Saloua, van Royen, Niels, Huys, Erik HJPG, Preijers, Frank WMB, Smeets, Esther MM, Aarntzen, Erik HJG, Zhang, Bowen, Li, Yang, Bremmers, Manita EJ, van der Velden, Walter JFM, Dolstra, Harry, Joosten, Leo AB, Gomes, Marc E, Netea, Mihai G, Riksen, Niels P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665893/ https://www.ncbi.nlm.nih.gov/pubmed/33168134 http://dx.doi.org/10.7554/eLife.60939

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