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Acupoint Catgut Embedding for Insomnia: A Meta-Analysis of Randomized Controlled Trials

OBJECTIVES: A Meta-analysis was carried out to evaluate the efficacy and safety of acupoint catgut embedding (ACE), a procedure of embedding sutures made of absorbable materials into the skin tissue of acupoints, on insomnia. METHODS: Relevant clinical randomized controlled trials (RCTs) were compre...

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Autores principales: Li, Wanrong, Li, Zhen, Zhang, Huixing, Wang, Yue, Chen, Hui, Xiong, Lize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665919/
https://www.ncbi.nlm.nih.gov/pubmed/33204287
http://dx.doi.org/10.1155/2020/5450824
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author Li, Wanrong
Li, Zhen
Zhang, Huixing
Wang, Yue
Chen, Hui
Xiong, Lize
author_facet Li, Wanrong
Li, Zhen
Zhang, Huixing
Wang, Yue
Chen, Hui
Xiong, Lize
author_sort Li, Wanrong
collection PubMed
description OBJECTIVES: A Meta-analysis was carried out to evaluate the efficacy and safety of acupoint catgut embedding (ACE), a procedure of embedding sutures made of absorbable materials into the skin tissue of acupoints, on insomnia. METHODS: Relevant clinical randomized controlled trials (RCTs) were comprehensively searched from eleven electronic databases (up to 1 March 2020). Two authors independently screened literature, extracted data, and assessed the risk of bias of included studies. Stata 12 and RevMan 5.3.0 software were used for meta-analysis. PyCharm 2019 and Gephi software (version 0.9.2) were used for complex network analysis. RESULTS: Thirty-four RCTs involving 2,655 patients were included. The meta-analysis suggested that ACE induced a better clinical efficacy compared with that in the estazolam tablets (EZ) group (RR = 1.22, 95% CI: 1.13, 1.31) or in the acupuncture (ACU) group (RR = 1.21, 95% CI: 1.14, 1.28) and could significantly reduce the score of Pittsburgh Sleep Quality Index (P < 0.05). ACE resulted in better long-term efficacy compared to that in the EZ group (RR = 1.87, 95% CI: 1.58, 2.22) and ACU group (RR = 1.30, 95% CI: 1.14, 1.48). ACE could significantly reduce the incidence of adverse events (RR = 0.30, 95% CI: 0.15, 0.60) compared with that in the EZ group. Complex network analysis indicated that acupoints of BL23, SP6, PC6, BL15, BL20, BL18, and HT7 were the core acupoints selected in ACE for insomnia. CONCLUSION: The clinical efficacy of ACE for insomnia is better than that of other interventions (EZ and ACU) in both short-term and long-term observations. Considering the efficacy and reduced visits to the clinic by ACE, the present study provides a practical and convenient complementary and alternative therapy for insomnia. This trial is registered with PROSPERO CRD 42020169866.
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spelling pubmed-76659192020-11-16 Acupoint Catgut Embedding for Insomnia: A Meta-Analysis of Randomized Controlled Trials Li, Wanrong Li, Zhen Zhang, Huixing Wang, Yue Chen, Hui Xiong, Lize Evid Based Complement Alternat Med Research Article OBJECTIVES: A Meta-analysis was carried out to evaluate the efficacy and safety of acupoint catgut embedding (ACE), a procedure of embedding sutures made of absorbable materials into the skin tissue of acupoints, on insomnia. METHODS: Relevant clinical randomized controlled trials (RCTs) were comprehensively searched from eleven electronic databases (up to 1 March 2020). Two authors independently screened literature, extracted data, and assessed the risk of bias of included studies. Stata 12 and RevMan 5.3.0 software were used for meta-analysis. PyCharm 2019 and Gephi software (version 0.9.2) were used for complex network analysis. RESULTS: Thirty-four RCTs involving 2,655 patients were included. The meta-analysis suggested that ACE induced a better clinical efficacy compared with that in the estazolam tablets (EZ) group (RR = 1.22, 95% CI: 1.13, 1.31) or in the acupuncture (ACU) group (RR = 1.21, 95% CI: 1.14, 1.28) and could significantly reduce the score of Pittsburgh Sleep Quality Index (P < 0.05). ACE resulted in better long-term efficacy compared to that in the EZ group (RR = 1.87, 95% CI: 1.58, 2.22) and ACU group (RR = 1.30, 95% CI: 1.14, 1.48). ACE could significantly reduce the incidence of adverse events (RR = 0.30, 95% CI: 0.15, 0.60) compared with that in the EZ group. Complex network analysis indicated that acupoints of BL23, SP6, PC6, BL15, BL20, BL18, and HT7 were the core acupoints selected in ACE for insomnia. CONCLUSION: The clinical efficacy of ACE for insomnia is better than that of other interventions (EZ and ACU) in both short-term and long-term observations. Considering the efficacy and reduced visits to the clinic by ACE, the present study provides a practical and convenient complementary and alternative therapy for insomnia. This trial is registered with PROSPERO CRD 42020169866. Hindawi 2020-11-06 /pmc/articles/PMC7665919/ /pubmed/33204287 http://dx.doi.org/10.1155/2020/5450824 Text en Copyright © 2020 Wanrong Li et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Li, Wanrong
Li, Zhen
Zhang, Huixing
Wang, Yue
Chen, Hui
Xiong, Lize
Acupoint Catgut Embedding for Insomnia: A Meta-Analysis of Randomized Controlled Trials
title Acupoint Catgut Embedding for Insomnia: A Meta-Analysis of Randomized Controlled Trials
title_full Acupoint Catgut Embedding for Insomnia: A Meta-Analysis of Randomized Controlled Trials
title_fullStr Acupoint Catgut Embedding for Insomnia: A Meta-Analysis of Randomized Controlled Trials
title_full_unstemmed Acupoint Catgut Embedding for Insomnia: A Meta-Analysis of Randomized Controlled Trials
title_short Acupoint Catgut Embedding for Insomnia: A Meta-Analysis of Randomized Controlled Trials
title_sort acupoint catgut embedding for insomnia: a meta-analysis of randomized controlled trials
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665919/
https://www.ncbi.nlm.nih.gov/pubmed/33204287
http://dx.doi.org/10.1155/2020/5450824
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