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Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study
The analysis of the effects of autozygosity, measured as the change of the mean value of a trait among offspring of genetic relatives, reveals the existence of directional dominance or overdominance. In this study we detect evidence of the effect of autozygosity in 4 out of 13 cardiometabolic diseas...
Autores principales: | Ceballos, Francisco C., Hazelhurst, Scott, Clark, David W., Agongo, Godfred, Asiki, Gershim, Boua, Palwende R., Xavier Gómez-Olivé, F., Mashinya, Felistas, Norris, Shane, Wilson, James F., Ramsay, Michèle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666169/ https://www.ncbi.nlm.nih.gov/pubmed/33188201 http://dx.doi.org/10.1038/s41467-020-19595-y |
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