Quantifying the efficacy of checkpoint inhibitors on CD8(+) cytotoxic T cells for immunotherapeutic applications via single-cell interaction

The inhibition of the PD1/PDL1 pathway has led to remarkable clinical success for cancer treatment in some patients. Many, however, exhibit little to no response to this treatment. To increase the efficacy of PD1 inhibition, additional checkpoint inhibitors are being explored as combination therapy...

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Detalles Bibliográficos
Autores principales: Sullivan, Matthew Ryan, Ugolini, Giovanni Stefano, Sarkar, Saheli, Kang, Wenjing, Smith, Evan Carlton, Mckenney, Seamus, Konry, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666200/
https://www.ncbi.nlm.nih.gov/pubmed/33188167
http://dx.doi.org/10.1038/s41419-020-03173-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666200/
https://www.ncbi.nlm.nih.gov/pubmed/33188167
http://dx.doi.org/10.1038/s41419-020-03173-7

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