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Characterisation of CD4+ T-cell subtypes using single cell RNA sequencing and the impact of cell number and sequencing depth

CD4+ T-cells represent a heterogeneous collection of specialised sub-types and are a key cell type in the pathogenesis of many diseases due to their role in the adaptive immune system. By investigating CD4+ T-cells at the single cell level, using RNA sequencing (scRNA-seq), there is the potential to...

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Detalles Bibliográficos
Autores principales: Ding, James, Smith, Samantha L., Orozco, Gisela, Barton, Anne, Eyre, Steve, Martin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666207/
https://www.ncbi.nlm.nih.gov/pubmed/33188258
http://dx.doi.org/10.1038/s41598-020-76972-9

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