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Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt–Jakob disease

Prion diseases are fatal and transmissible neurodegenerative disorders caused by the misfolding and aggregation of prion protein. Although recent studies have implicated epigenetic variation in common neurodegenerative disorders, no study has yet explored their role in human prion diseases. Here we...

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Detalles Bibliográficos
Autores principales: Dabin, Luke C., Guntoro, Fernando, Campbell, Tracy, Bélicard, Tony, Smith, Adam R., Smith, Rebecca G., Raybould, Rachel, Schott, Jonathan M., Lunnon, Katie, Sarkies, Peter, Collinge, John, Mead, Simon, Viré, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666287/
https://www.ncbi.nlm.nih.gov/pubmed/32918118
http://dx.doi.org/10.1007/s00401-020-02224-9