Cargando…
Metastatic melanoma of unknown origin mimicking neurofibromatosis
We present an unusual case of metastatic melanoma in a young patient with imaging appearance resembling neurofibromatosis. A 36-year-old-man with a history of cervical radiculopathy presented with cauda equina syndrome. An MRI was performed for further evaluation demonstrating multiple intradural, e...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666308/ https://www.ncbi.nlm.nih.gov/pubmed/33224396 http://dx.doi.org/10.1016/j.radcr.2020.08.034 |
_version_ | 1783610106398638080 |
---|---|
author | Chen, Lauren Newby, Celeste Fakhri, Nibras Lammle, Markus |
author_facet | Chen, Lauren Newby, Celeste Fakhri, Nibras Lammle, Markus |
author_sort | Chen, Lauren |
collection | PubMed |
description | We present an unusual case of metastatic melanoma in a young patient with imaging appearance resembling neurofibromatosis. A 36-year-old-man with a history of cervical radiculopathy presented with cauda equina syndrome. An MRI was performed for further evaluation demonstrating multiple intradural, extramedullary enhancing lesions in the thoracic and lumbar spine, as well as extra-axial enhancing lesions with involvement of the lateral ventricles and posterior fossa. Bilateral pulmonary masses were found on chest CT. Lung lesions were biopsied and positive for metastatic melanoma. Melanoma is the third most common primary neoplasm to produce brain metastasis and should be considered on the differential as a cause of newly detected intracranial and intraspinal masses in young patients. |
format | Online Article Text |
id | pubmed-7666308 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-76663082020-11-20 Metastatic melanoma of unknown origin mimicking neurofibromatosis Chen, Lauren Newby, Celeste Fakhri, Nibras Lammle, Markus Radiol Case Rep Case Report We present an unusual case of metastatic melanoma in a young patient with imaging appearance resembling neurofibromatosis. A 36-year-old-man with a history of cervical radiculopathy presented with cauda equina syndrome. An MRI was performed for further evaluation demonstrating multiple intradural, extramedullary enhancing lesions in the thoracic and lumbar spine, as well as extra-axial enhancing lesions with involvement of the lateral ventricles and posterior fossa. Bilateral pulmonary masses were found on chest CT. Lung lesions were biopsied and positive for metastatic melanoma. Melanoma is the third most common primary neoplasm to produce brain metastasis and should be considered on the differential as a cause of newly detected intracranial and intraspinal masses in young patients. Elsevier 2020-11-10 /pmc/articles/PMC7666308/ /pubmed/33224396 http://dx.doi.org/10.1016/j.radcr.2020.08.034 Text en © 2020 Published by Elsevier Inc. on behalf of University of Washington. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Chen, Lauren Newby, Celeste Fakhri, Nibras Lammle, Markus Metastatic melanoma of unknown origin mimicking neurofibromatosis |
title | Metastatic melanoma of unknown origin mimicking neurofibromatosis |
title_full | Metastatic melanoma of unknown origin mimicking neurofibromatosis |
title_fullStr | Metastatic melanoma of unknown origin mimicking neurofibromatosis |
title_full_unstemmed | Metastatic melanoma of unknown origin mimicking neurofibromatosis |
title_short | Metastatic melanoma of unknown origin mimicking neurofibromatosis |
title_sort | metastatic melanoma of unknown origin mimicking neurofibromatosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666308/ https://www.ncbi.nlm.nih.gov/pubmed/33224396 http://dx.doi.org/10.1016/j.radcr.2020.08.034 |
work_keys_str_mv | AT chenlauren metastaticmelanomaofunknownoriginmimickingneurofibromatosis AT newbyceleste metastaticmelanomaofunknownoriginmimickingneurofibromatosis AT fakhrinibras metastaticmelanomaofunknownoriginmimickingneurofibromatosis AT lammlemarkus metastaticmelanomaofunknownoriginmimickingneurofibromatosis |