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Metastatic melanoma of unknown origin mimicking neurofibromatosis

We present an unusual case of metastatic melanoma in a young patient with imaging appearance resembling neurofibromatosis. A 36-year-old-man with a history of cervical radiculopathy presented with cauda equina syndrome. An MRI was performed for further evaluation demonstrating multiple intradural, e...

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Autores principales: Chen, Lauren, Newby, Celeste, Fakhri, Nibras, Lammle, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666308/
https://www.ncbi.nlm.nih.gov/pubmed/33224396
http://dx.doi.org/10.1016/j.radcr.2020.08.034
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author Chen, Lauren
Newby, Celeste
Fakhri, Nibras
Lammle, Markus
author_facet Chen, Lauren
Newby, Celeste
Fakhri, Nibras
Lammle, Markus
author_sort Chen, Lauren
collection PubMed
description We present an unusual case of metastatic melanoma in a young patient with imaging appearance resembling neurofibromatosis. A 36-year-old-man with a history of cervical radiculopathy presented with cauda equina syndrome. An MRI was performed for further evaluation demonstrating multiple intradural, extramedullary enhancing lesions in the thoracic and lumbar spine, as well as extra-axial enhancing lesions with involvement of the lateral ventricles and posterior fossa. Bilateral pulmonary masses were found on chest CT. Lung lesions were biopsied and positive for metastatic melanoma. Melanoma is the third most common primary neoplasm to produce brain metastasis and should be considered on the differential as a cause of newly detected intracranial and intraspinal masses in young patients.
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spelling pubmed-76663082020-11-20 Metastatic melanoma of unknown origin mimicking neurofibromatosis Chen, Lauren Newby, Celeste Fakhri, Nibras Lammle, Markus Radiol Case Rep Case Report We present an unusual case of metastatic melanoma in a young patient with imaging appearance resembling neurofibromatosis. A 36-year-old-man with a history of cervical radiculopathy presented with cauda equina syndrome. An MRI was performed for further evaluation demonstrating multiple intradural, extramedullary enhancing lesions in the thoracic and lumbar spine, as well as extra-axial enhancing lesions with involvement of the lateral ventricles and posterior fossa. Bilateral pulmonary masses were found on chest CT. Lung lesions were biopsied and positive for metastatic melanoma. Melanoma is the third most common primary neoplasm to produce brain metastasis and should be considered on the differential as a cause of newly detected intracranial and intraspinal masses in young patients. Elsevier 2020-11-10 /pmc/articles/PMC7666308/ /pubmed/33224396 http://dx.doi.org/10.1016/j.radcr.2020.08.034 Text en © 2020 Published by Elsevier Inc. on behalf of University of Washington. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Chen, Lauren
Newby, Celeste
Fakhri, Nibras
Lammle, Markus
Metastatic melanoma of unknown origin mimicking neurofibromatosis
title Metastatic melanoma of unknown origin mimicking neurofibromatosis
title_full Metastatic melanoma of unknown origin mimicking neurofibromatosis
title_fullStr Metastatic melanoma of unknown origin mimicking neurofibromatosis
title_full_unstemmed Metastatic melanoma of unknown origin mimicking neurofibromatosis
title_short Metastatic melanoma of unknown origin mimicking neurofibromatosis
title_sort metastatic melanoma of unknown origin mimicking neurofibromatosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666308/
https://www.ncbi.nlm.nih.gov/pubmed/33224396
http://dx.doi.org/10.1016/j.radcr.2020.08.034
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