Methylation of the Promoter Region of the Tight Junction Protein-1 by DNMT1 Induces EMT-like Features in Multiple Myeloma

The molecular alterations that initiate the development of multiple myeloma (MM) are not fully understood. Our results revealed that TJP1 was downregulated in MM and positively related to the overall survival of MM patients in The Cancer Genome Atlas (TCGA) database and patient samples. In parallel,...

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Detalles Bibliográficos
Autores principales: Li, Miao, Qi, Lin, Xu, Jing-Bo, Zhong, Li-Ye, Chan, Szehoi, Chen, Shu-Na, Shao, Xin-Rong, Zheng, Li-Yuan, Dong, Zhao-Xia, Fang, Tian-Liang, Mai, Zhi-Ying, Li, Juan, Zheng, Yongjiang, Zhang, Xing-Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666313/
https://www.ncbi.nlm.nih.gov/pubmed/33251332
http://dx.doi.org/10.1016/j.omto.2020.10.004

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