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Upregulated CBX8 Promotes Cancer Metastasis via the WNK2/MMP2 Pathway

Metastasis is associated with poor prognosis in cancer and is a multistep process that includes invasion and migration. Several epigenetic factors are involved in this process, including chromobox protein homolog 8 (CBX8). Here, we show that CBX8 is overexpressed in many cancers compared with normal...

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Detalles Bibliográficos
Autores principales: Jia, Yongsheng, Wang, Yujun, Zhang, Cuicui, Chen, Mike Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666318/
https://www.ncbi.nlm.nih.gov/pubmed/33251331
http://dx.doi.org/10.1016/j.omto.2020.09.012