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Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy

INTRODUCTION: We aimed at exploring the proportion of patients dying with COVID‐19 and concomitant dementia in Italy, as well as their clinical characteristics and trajectories of care. METHODS: The proportion of COVID‐19‐related deaths occurring in people with dementia and the clinical characterist...

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Autores principales: Canevelli, Marco, Palmieri, Luigi, Raparelli, Valeria, Lo Noce, Cinzia, Colaizzo, Elisa, Tiple, Dorina, Vaianella, Luana, Vanacore, Nicola, Brusaferro, Silvio, Onder, Graziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666428/
https://www.ncbi.nlm.nih.gov/pubmed/33225041
http://dx.doi.org/10.1002/dad2.12114
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author Canevelli, Marco
Palmieri, Luigi
Raparelli, Valeria
Lo Noce, Cinzia
Colaizzo, Elisa
Tiple, Dorina
Vaianella, Luana
Vanacore, Nicola
Brusaferro, Silvio
Onder, Graziano
author_facet Canevelli, Marco
Palmieri, Luigi
Raparelli, Valeria
Lo Noce, Cinzia
Colaizzo, Elisa
Tiple, Dorina
Vaianella, Luana
Vanacore, Nicola
Brusaferro, Silvio
Onder, Graziano
author_sort Canevelli, Marco
collection PubMed
description INTRODUCTION: We aimed at exploring the proportion of patients dying with COVID‐19 and concomitant dementia in Italy, as well as their clinical characteristics and trajectories of care. METHODS: The proportion of COVID‐19‐related deaths occurring in people with dementia and the clinical characteristics of deceased individuals according to their dementia status were explored by considering the medical charts of a representative sample of patients deceased in Italian hospitals (n = 2621). RESULTS: A total of 415 individuals with dementia were identified in the study population, accounting for 15.8% of overall COVID‐19‐related deaths. Patients with dementia less frequently presented with cough, had lower chance of receiving supportive therapies and intensive care approaches, and showed a faster clinical worsening as compared with individuals with intact cognition. DISCUSSION: Dementia confers a relevant risk of adverse outcomes in case of SARS‐CoV‐2 infection and influences the clinical presentation, course and management of affected individuals.
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spelling pubmed-76664282020-11-20 Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy Canevelli, Marco Palmieri, Luigi Raparelli, Valeria Lo Noce, Cinzia Colaizzo, Elisa Tiple, Dorina Vaianella, Luana Vanacore, Nicola Brusaferro, Silvio Onder, Graziano Alzheimers Dement (Amst) Diagnostic Assessment & Prognosis INTRODUCTION: We aimed at exploring the proportion of patients dying with COVID‐19 and concomitant dementia in Italy, as well as their clinical characteristics and trajectories of care. METHODS: The proportion of COVID‐19‐related deaths occurring in people with dementia and the clinical characteristics of deceased individuals according to their dementia status were explored by considering the medical charts of a representative sample of patients deceased in Italian hospitals (n = 2621). RESULTS: A total of 415 individuals with dementia were identified in the study population, accounting for 15.8% of overall COVID‐19‐related deaths. Patients with dementia less frequently presented with cough, had lower chance of receiving supportive therapies and intensive care approaches, and showed a faster clinical worsening as compared with individuals with intact cognition. DISCUSSION: Dementia confers a relevant risk of adverse outcomes in case of SARS‐CoV‐2 infection and influences the clinical presentation, course and management of affected individuals. John Wiley and Sons Inc. 2020-11-14 /pmc/articles/PMC7666428/ /pubmed/33225041 http://dx.doi.org/10.1002/dad2.12114 Text en © 2020 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Diagnostic Assessment & Prognosis
Canevelli, Marco
Palmieri, Luigi
Raparelli, Valeria
Lo Noce, Cinzia
Colaizzo, Elisa
Tiple, Dorina
Vaianella, Luana
Vanacore, Nicola
Brusaferro, Silvio
Onder, Graziano
Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy
title Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy
title_full Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy
title_fullStr Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy
title_full_unstemmed Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy
title_short Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy
title_sort prevalence and clinical correlates of dementia among covid‐19‐related deaths in italy
topic Diagnostic Assessment & Prognosis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666428/
https://www.ncbi.nlm.nih.gov/pubmed/33225041
http://dx.doi.org/10.1002/dad2.12114
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