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Fast and accurate structure probability estimation for simultaneous alignment and folding of RNAs with Markov chains
MOTIVATION: Simultaneous alignment and folding (SA&F) of RNAs is the indispensable gold standard for inferring the structure of non-coding RNAs and their general analysis. The original algorithm, proposed by Sankoff, solves the theoretical problem exactly with a complexity of [Formula: see text]...
Autores principales: | Miladi, Milad, Raden, Martin, Will, Sebastian, Backofen, Rolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666477/ https://www.ncbi.nlm.nih.gov/pubmed/33292340 http://dx.doi.org/10.1186/s13015-020-00179-w |
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