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Increased H3K4me3 methylation and decreased miR-7113-5p expression lead to enhanced Wnt/β-catenin signaling in immune cells from PTSD patients leading to inflammatory phenotype

BACKGROUND: Posttraumatic stress disorder (PTSD) is a psychiatric disorder accompanied by chronic peripheral inflammation. What triggers inflammation in PTSD is currently unclear. In the present study, we identified potential defects in signaling pathways in peripheral blood mononuclear cells (PBMCs...

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Detalles Bibliográficos
Autores principales:	Bam, Marpe, Yang, Xiaoming, Busbee, Brandon P., Aiello, Allison E., Uddin, Monica, Ginsberg, Jay P., Galea, Sandro, Nagarkatti, Prakash S., Nagarkatti, Mitzi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666486/ https://www.ncbi.nlm.nih.gov/pubmed/33189141 http://dx.doi.org/10.1186/s10020-020-00238-3

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