WNT signaling suppresses oligodendrogenesis via Ngn2-dependent direct inhibition of Olig2 expression

Olig2 transcription factor is essential for the maintenance of neural progenitor cells (NPCs) in the pMN domain and their sequential specification into motor neurons (MNs) and oligodendrocyte precursor cells (OPCs). The expression of Olig2 rapidly declines in newly generated MNs. However, Olig2 expr...

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Detalles Bibliográficos
Autores principales: Jiang, Min, Yu, Dan, Xie, Binghua, Huang, Hao, Lu, Wenwen, Qiu, Mengsheng, Dai, Zhong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666497/
https://www.ncbi.nlm.nih.gov/pubmed/33187539
http://dx.doi.org/10.1186/s13041-020-00696-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666497/
https://www.ncbi.nlm.nih.gov/pubmed/33187539
http://dx.doi.org/10.1186/s13041-020-00696-0

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