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DLDTI: a learning-based framework for drug-target interaction identification using neural networks and network representation

BACKGROUND: Drug repositioning, the strategy of unveiling novel targets of existing drugs could reduce costs and accelerate the pace of drug development. To elucidate the novel molecular mechanism of known drugs, considering the long time and high cost of experimental determination, the efficient an...

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Detalles Bibliográficos
Autores principales: Zhao, Yihan, Zheng, Kai, Guan, Baoyi, Guo, Mengmeng, Song, Lei, Gao, Jie, Qu, Hua, Wang, Yuhui, Shi, Dazhuo, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666529/
https://www.ncbi.nlm.nih.gov/pubmed/33187537
http://dx.doi.org/10.1186/s12967-020-02602-7