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DLDTI: a learning-based framework for drug-target interaction identification using neural networks and network representation
BACKGROUND: Drug repositioning, the strategy of unveiling novel targets of existing drugs could reduce costs and accelerate the pace of drug development. To elucidate the novel molecular mechanism of known drugs, considering the long time and high cost of experimental determination, the efficient an...
Autores principales: | Zhao, Yihan, Zheng, Kai, Guan, Baoyi, Guo, Mengmeng, Song, Lei, Gao, Jie, Qu, Hua, Wang, Yuhui, Shi, Dazhuo, Zhang, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666529/ https://www.ncbi.nlm.nih.gov/pubmed/33187537 http://dx.doi.org/10.1186/s12967-020-02602-7 |
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