Cargando…

Seguimiento inmunológico después de trasplante renal: una propuesta para la práctica clínica en Colombia

Graft damage is a process that starts at the moment of transplantation, due to comorbidities of receptor, donor status, ischemia time, ischemia-reperfusion phenomenon, among others, those induce metabolic and immune factors that ultimately trigger clinical manifestations of graft dysfunction. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortiz, Melissa Andrea, Álvarez, Cristiam Mauricio, Arrunátegui, Ana María, Arias, Yazmín Rocío, Villegas, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Nacional de Salud 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666855/
https://www.ncbi.nlm.nih.gov/pubmed/33030826
http://dx.doi.org/10.7705/biomedica.5092
Descripción
Sumario:Graft damage is a process that starts at the moment of transplantation, due to comorbidities of receptor, donor status, ischemia time, ischemia-reperfusion phenomenon, among others, those induce metabolic and immune factors that ultimately trigger clinical manifestations of graft dysfunction. However, the preclinical progression between the time of transplantation and the appearance of signs and symptoms of graft damage can take weeks to years. Therefore, the implementation of rational monitoring approaches during the posttransplantation period is critical and should include not only the clinical follow-up but also anticipate immunological graft damage. In the present essay, we propose an immunological monitoring algorithm for the post-renal transplantation period.