Histone Deacetylase 3 Aggravates Type 1 Diabetes Mellitus by Inhibiting Lymphocyte Apoptosis Through the microRNA-296-5p/Bcl-xl Axis

Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease characterized by immune-mediated destruction of pancreatic beta-cells. Multiple microRNAs (miRNAs) have been implicated in T1DM pathogenesis. Although histone deacetylase 3 (HDAC3) has been reported to be involved in T1DM, the underlyin...

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Detalles Bibliográficos
Autores principales: Hu, Qibo, Che, Guanghua, Yang, Yu, Xie, Hongchang, Tian, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667129/
https://www.ncbi.nlm.nih.gov/pubmed/33240312
http://dx.doi.org/10.3389/fgene.2020.536854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667129/
https://www.ncbi.nlm.nih.gov/pubmed/33240312
http://dx.doi.org/10.3389/fgene.2020.536854

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