The Interplay Between Beta-Amyloid 1–42 (Aβ(1–42))-Induced Hippocampal Inflammatory Response, p-tau, Vascular Pathology, and Their Synergistic Contributions to Neuronal Death and Behavioral Deficits

Alzheimer’s disease (AD), the most common chronic neurodegenerative disorder, has complex neuropathology. The principal neuropathological hallmarks of the disease are the deposition of extracellular β-amyloid (Aβ) plaques and neurofibrillary tangles (NFTs) comprised of hyperphosphorylated tau (p-tau...

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Detalles Bibliográficos
Autores principales: Calvo-Flores Guzmán, Beatriz, Elizabeth Chaffey, Tessa, Hansika Palpagama, Thulani, Waters, Sarah, Boix, Jordi, Tate, Warren Perry, Peppercorn, Katie, Dragunow, Michael, Waldvogel, Henry John, Faull, Richard Lewis Maxwell, Kwakowsky, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667153/
https://www.ncbi.nlm.nih.gov/pubmed/33224025
http://dx.doi.org/10.3389/fnmol.2020.552073

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