A small natural molecule CADPE kills residual colorectal cancer cells by inhibiting key transcription factors and translation initiation factors

Residual disease is the major cause for colorectal cancer (CRC) relapse. Herein, we explore whether and how a natural molecule CADPE killed heterogenic populations in a panel of CRC cell lines with KRAS/BRAF mutations that are natively resistant to EGFR- or VEGFR-targeted therapy, without sparing pe...

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Detalles Bibliográficos
Autores principales: Zheng, Guo-Wan, Tang, Ming-Min, Shu, Chen-Yan, Xin, Wen-Xiu, Zhang, Yan-Hua, Chi, Bin-Bin, Shi, Mu-Ran, Guo, Xing, Zhang, Zhi-Zhen, Lian, Xiao-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667164/
https://www.ncbi.nlm.nih.gov/pubmed/33191401
http://dx.doi.org/10.1038/s41419-020-03191-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667164/
https://www.ncbi.nlm.nih.gov/pubmed/33191401
http://dx.doi.org/10.1038/s41419-020-03191-5

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