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Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis

INTRODUCTION: The early recognition and management of the behavioral and psychological symptoms of dementia (BPSD) are important to inform treatment decisions. Current BPSD screening tools are time‐consuming and require advanced skills, limiting their application in routine clinical practice. An eas...

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Autores principales: Phannarus, Harisd, Muangpaisan, Weerasak, Siritipakorn, Pitiporn, Pianchob, Sudarat, Supapueng, Orawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667320/
https://www.ncbi.nlm.nih.gov/pubmed/32857486
http://dx.doi.org/10.1002/brb3.1816
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author Phannarus, Harisd
Muangpaisan, Weerasak
Siritipakorn, Pitiporn
Pianchob, Sudarat
Supapueng, Orawan
author_facet Phannarus, Harisd
Muangpaisan, Weerasak
Siritipakorn, Pitiporn
Pianchob, Sudarat
Supapueng, Orawan
author_sort Phannarus, Harisd
collection PubMed
description INTRODUCTION: The early recognition and management of the behavioral and psychological symptoms of dementia (BPSD) are important to inform treatment decisions. Current BPSD screening tools are time‐consuming and require advanced skills, limiting their application in routine clinical practice. An easier and quicker tool for use by nonphysician healthcare personnel is needed. METHODS: A 14‐item, Thai‐language, BPSD scoring system for dementia (BPSD‐T) was developed, based on clinical surveys and modifications after a pilot study. The Neuropsychiatric Inventory (NPI), BPSD‐T, Thai Mental State Examination (TMSE), Clinical Dementia Rating Scale (CDR), and Barthel Index were performed. BPSD‐T and NPI scores were compared, and test validity and reliability were analyzed. RESULTS: A total of 168 people with dementia (mean age, 80.7 ± 6.7 years) and their primary caregivers were recruited. A total of 105 (62.5%) subjects were diagnosed with Alzheimer's disease (AD), and 31 (18.5%) with AD with small‐vessel disease. The Global CDR was 0.5–1 for 73.8% of subjects, and 2–3 for 26.2%. The BPSD‐T content validity index was 0.80–0.98, with high inter‐rater and test–retest reliability. Confirmatory factor analysis showed the goodness of fit of 5 clusters of BPSD‐T included a psychomotor syndrome (aggression, irritability, delusions, insomnia), an affective syndrome (apathy, repeating, anxiety, depression), a psychosis syndrome (misidentification, hallucinations), a behavior syndrome (hoarding, rummaging, wandering), and a euphoria syndrome (euphoria). Convergent validity showed a high correlation of the frequency score (r = 0.66) and caregiver distress score (r = 0.76) with the NPI. The BPSD‐T score was significantly higher with more severe dementia. The average completion time for the BPSD‐T (230.9 ± 65.5 s) was significantly less than that for NPI (506 ± 196.9 s; p < .001). CONCLUSIONS: BPSD‐T is a quick, reliable, and valid test to evaluate BPSD from the common dementia subtypes and severity, with a good correlation with the NPI. Its application in routine clinical practice will enable earlier recognition, targeted intervention, improved quality of care, and reduced caregiver burden.
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spelling pubmed-76673202020-11-20 Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis Phannarus, Harisd Muangpaisan, Weerasak Siritipakorn, Pitiporn Pianchob, Sudarat Supapueng, Orawan Brain Behav Original Research INTRODUCTION: The early recognition and management of the behavioral and psychological symptoms of dementia (BPSD) are important to inform treatment decisions. Current BPSD screening tools are time‐consuming and require advanced skills, limiting their application in routine clinical practice. An easier and quicker tool for use by nonphysician healthcare personnel is needed. METHODS: A 14‐item, Thai‐language, BPSD scoring system for dementia (BPSD‐T) was developed, based on clinical surveys and modifications after a pilot study. The Neuropsychiatric Inventory (NPI), BPSD‐T, Thai Mental State Examination (TMSE), Clinical Dementia Rating Scale (CDR), and Barthel Index were performed. BPSD‐T and NPI scores were compared, and test validity and reliability were analyzed. RESULTS: A total of 168 people with dementia (mean age, 80.7 ± 6.7 years) and their primary caregivers were recruited. A total of 105 (62.5%) subjects were diagnosed with Alzheimer's disease (AD), and 31 (18.5%) with AD with small‐vessel disease. The Global CDR was 0.5–1 for 73.8% of subjects, and 2–3 for 26.2%. The BPSD‐T content validity index was 0.80–0.98, with high inter‐rater and test–retest reliability. Confirmatory factor analysis showed the goodness of fit of 5 clusters of BPSD‐T included a psychomotor syndrome (aggression, irritability, delusions, insomnia), an affective syndrome (apathy, repeating, anxiety, depression), a psychosis syndrome (misidentification, hallucinations), a behavior syndrome (hoarding, rummaging, wandering), and a euphoria syndrome (euphoria). Convergent validity showed a high correlation of the frequency score (r = 0.66) and caregiver distress score (r = 0.76) with the NPI. The BPSD‐T score was significantly higher with more severe dementia. The average completion time for the BPSD‐T (230.9 ± 65.5 s) was significantly less than that for NPI (506 ± 196.9 s; p < .001). CONCLUSIONS: BPSD‐T is a quick, reliable, and valid test to evaluate BPSD from the common dementia subtypes and severity, with a good correlation with the NPI. Its application in routine clinical practice will enable earlier recognition, targeted intervention, improved quality of care, and reduced caregiver burden. John Wiley and Sons Inc. 2020-08-28 /pmc/articles/PMC7667320/ /pubmed/32857486 http://dx.doi.org/10.1002/brb3.1816 Text en © 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Phannarus, Harisd
Muangpaisan, Weerasak
Siritipakorn, Pitiporn
Pianchob, Sudarat
Supapueng, Orawan
Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis
title Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis
title_full Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis
title_fullStr Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis
title_full_unstemmed Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis
title_short Development of a Thai tool for assessing behavioral and psychological symptoms of dementia: A confirmatory factor analysis
title_sort development of a thai tool for assessing behavioral and psychological symptoms of dementia: a confirmatory factor analysis
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667320/
https://www.ncbi.nlm.nih.gov/pubmed/32857486
http://dx.doi.org/10.1002/brb3.1816
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