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Epidemiology of Myasthenia Gravis in Sweden 2006–2016
INTRODUCTION: Reported incidence and prevalence rates of Myasthenia Gravis (MG) vary widely and are assumed to have increased over the last few decades. We conducted a nationwide register‐based study on the current incidence and prevalence of MG and MG subgroups in Sweden. METHODS: Data were acquire...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667338/ https://www.ncbi.nlm.nih.gov/pubmed/32869520 http://dx.doi.org/10.1002/brb3.1819 |
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author | Westerberg, Elisabet Punga, Anna Rostedt |
author_facet | Westerberg, Elisabet Punga, Anna Rostedt |
author_sort | Westerberg, Elisabet |
collection | PubMed |
description | INTRODUCTION: Reported incidence and prevalence rates of Myasthenia Gravis (MG) vary widely and are assumed to have increased over the last few decades. We conducted a nationwide register‐based study on the current incidence and prevalence of MG and MG subgroups in Sweden. METHODS: Data were acquired from four Swedish Health Registers in order to identify patients with MG. Incidence and prevalence rates were calculated for the years 2006–2016, using population numbers provided by Statistics Sweden. RESULTS: In 2016, the incidence of MG in Sweden was 2.9 per 100,000 inhabitants (95% CI: 2.5–3.2/100,000) and the crude prevalence was 36.1 per 100,000 inhabitants (95% CI: 34.9–37.3). There was a significant increase in Myasthenia Gravis prevalence from 2006 to 2016. Prevalence rates of all MG subgroups but thymoma‐associated MG increased over the same period of time. CONCLUSIONS: The incidence and prevalence of Myasthenia Gravis have increased over time in Sweden, and the rates are high in comparison with other countries. |
format | Online Article Text |
id | pubmed-7667338 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76673382020-11-20 Epidemiology of Myasthenia Gravis in Sweden 2006–2016 Westerberg, Elisabet Punga, Anna Rostedt Brain Behav Original Research INTRODUCTION: Reported incidence and prevalence rates of Myasthenia Gravis (MG) vary widely and are assumed to have increased over the last few decades. We conducted a nationwide register‐based study on the current incidence and prevalence of MG and MG subgroups in Sweden. METHODS: Data were acquired from four Swedish Health Registers in order to identify patients with MG. Incidence and prevalence rates were calculated for the years 2006–2016, using population numbers provided by Statistics Sweden. RESULTS: In 2016, the incidence of MG in Sweden was 2.9 per 100,000 inhabitants (95% CI: 2.5–3.2/100,000) and the crude prevalence was 36.1 per 100,000 inhabitants (95% CI: 34.9–37.3). There was a significant increase in Myasthenia Gravis prevalence from 2006 to 2016. Prevalence rates of all MG subgroups but thymoma‐associated MG increased over the same period of time. CONCLUSIONS: The incidence and prevalence of Myasthenia Gravis have increased over time in Sweden, and the rates are high in comparison with other countries. John Wiley and Sons Inc. 2020-09-01 /pmc/articles/PMC7667338/ /pubmed/32869520 http://dx.doi.org/10.1002/brb3.1819 Text en © 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Westerberg, Elisabet Punga, Anna Rostedt Epidemiology of Myasthenia Gravis in Sweden 2006–2016 |
title | Epidemiology of Myasthenia Gravis in Sweden 2006–2016 |
title_full | Epidemiology of Myasthenia Gravis in Sweden 2006–2016 |
title_fullStr | Epidemiology of Myasthenia Gravis in Sweden 2006–2016 |
title_full_unstemmed | Epidemiology of Myasthenia Gravis in Sweden 2006–2016 |
title_short | Epidemiology of Myasthenia Gravis in Sweden 2006–2016 |
title_sort | epidemiology of myasthenia gravis in sweden 2006–2016 |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667338/ https://www.ncbi.nlm.nih.gov/pubmed/32869520 http://dx.doi.org/10.1002/brb3.1819 |
work_keys_str_mv | AT westerbergelisabet epidemiologyofmyastheniagravisinsweden20062016 AT pungaannarostedt epidemiologyofmyastheniagravisinsweden20062016 |