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Epidemiology of Myasthenia Gravis in Sweden 2006–2016

INTRODUCTION: Reported incidence and prevalence rates of Myasthenia Gravis (MG) vary widely and are assumed to have increased over the last few decades. We conducted a nationwide register‐based study on the current incidence and prevalence of MG and MG subgroups in Sweden. METHODS: Data were acquire...

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Detalles Bibliográficos
Autores principales: Westerberg, Elisabet, Punga, Anna Rostedt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667338/
https://www.ncbi.nlm.nih.gov/pubmed/32869520
http://dx.doi.org/10.1002/brb3.1819
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author Westerberg, Elisabet
Punga, Anna Rostedt
author_facet Westerberg, Elisabet
Punga, Anna Rostedt
author_sort Westerberg, Elisabet
collection PubMed
description INTRODUCTION: Reported incidence and prevalence rates of Myasthenia Gravis (MG) vary widely and are assumed to have increased over the last few decades. We conducted a nationwide register‐based study on the current incidence and prevalence of MG and MG subgroups in Sweden. METHODS: Data were acquired from four Swedish Health Registers in order to identify patients with MG. Incidence and prevalence rates were calculated for the years 2006–2016, using population numbers provided by Statistics Sweden. RESULTS: In 2016, the incidence of MG in Sweden was 2.9 per 100,000 inhabitants (95% CI: 2.5–3.2/100,000) and the crude prevalence was 36.1 per 100,000 inhabitants (95% CI: 34.9–37.3). There was a significant increase in Myasthenia Gravis prevalence from 2006 to 2016. Prevalence rates of all MG subgroups but thymoma‐associated MG increased over the same period of time. CONCLUSIONS: The incidence and prevalence of Myasthenia Gravis have increased over time in Sweden, and the rates are high in comparison with other countries.
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spelling pubmed-76673382020-11-20 Epidemiology of Myasthenia Gravis in Sweden 2006–2016 Westerberg, Elisabet Punga, Anna Rostedt Brain Behav Original Research INTRODUCTION: Reported incidence and prevalence rates of Myasthenia Gravis (MG) vary widely and are assumed to have increased over the last few decades. We conducted a nationwide register‐based study on the current incidence and prevalence of MG and MG subgroups in Sweden. METHODS: Data were acquired from four Swedish Health Registers in order to identify patients with MG. Incidence and prevalence rates were calculated for the years 2006–2016, using population numbers provided by Statistics Sweden. RESULTS: In 2016, the incidence of MG in Sweden was 2.9 per 100,000 inhabitants (95% CI: 2.5–3.2/100,000) and the crude prevalence was 36.1 per 100,000 inhabitants (95% CI: 34.9–37.3). There was a significant increase in Myasthenia Gravis prevalence from 2006 to 2016. Prevalence rates of all MG subgroups but thymoma‐associated MG increased over the same period of time. CONCLUSIONS: The incidence and prevalence of Myasthenia Gravis have increased over time in Sweden, and the rates are high in comparison with other countries. John Wiley and Sons Inc. 2020-09-01 /pmc/articles/PMC7667338/ /pubmed/32869520 http://dx.doi.org/10.1002/brb3.1819 Text en © 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Westerberg, Elisabet
Punga, Anna Rostedt
Epidemiology of Myasthenia Gravis in Sweden 2006–2016
title Epidemiology of Myasthenia Gravis in Sweden 2006–2016
title_full Epidemiology of Myasthenia Gravis in Sweden 2006–2016
title_fullStr Epidemiology of Myasthenia Gravis in Sweden 2006–2016
title_full_unstemmed Epidemiology of Myasthenia Gravis in Sweden 2006–2016
title_short Epidemiology of Myasthenia Gravis in Sweden 2006–2016
title_sort epidemiology of myasthenia gravis in sweden 2006–2016
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667338/
https://www.ncbi.nlm.nih.gov/pubmed/32869520
http://dx.doi.org/10.1002/brb3.1819
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