Two simple and rapid methods based on maximum diameter accurately estimate large lesion volumes in acute stroke

BACKGROUND: We compared two simple and rapid diameter‐based methods (ABC/2, od‐value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml. METHODS: In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthog...

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Detalles Bibliográficos
Autores principales: Kufner, Anna, Stief, Jonas, Siegerink, Bob, Nolte, Christian, Endres, Matthias, Fiebach, Jochen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667359/
https://www.ncbi.nlm.nih.gov/pubmed/32909402
http://dx.doi.org/10.1002/brb3.1828
Descripción
Sumario:BACKGROUND: We compared two simple and rapid diameter‐based methods (ABC/2, od‐value) in terms of their accuracy in predicting lesion volume >70 ml and >100 ml. METHODS: In 238 DWI images of ischemic stroke patients from the AXIS2 trial, maximum lesion diameter and corresponding maximum orthogonal diameter were measured. Estimation of infarct volume based on od‐value and ABC/2 calculation was compared to volumetric assessments. RESULTS: Accuracy of od‐value and ABC/2 was similar for >70 ml (92.0 vs. 87.4) and >100 ml (92.9 vs. 93.3). ABC/2 overestimated lesion volume by 29.9%, resulting in a lower specificity. CONCLUSIONS: Od‐value is a robust tool for patient selection in trials.

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