Cargando…
SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study
The route of transmission of Novel SARS-CoV-2 virus is ambiguous. In this regard we planned a study to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Indian Association of Medical Microbiologists. Published by Elsevier B.V.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667402/ https://www.ncbi.nlm.nih.gov/pubmed/33610243 http://dx.doi.org/10.1016/j.ijmmb.2020.10.012 |
_version_ | 1783610305363836928 |
---|---|
author | Prakash, Shantanu Shukla, Suruchi Mishra, Hricha Prakash, Om Khan, Danish N. Pandey, Ajay Reddy, D. Himanshu Jain, Amita |
author_facet | Prakash, Shantanu Shukla, Suruchi Mishra, Hricha Prakash, Om Khan, Danish N. Pandey, Ajay Reddy, D. Himanshu Jain, Amita |
author_sort | Prakash, Shantanu |
collection | PubMed |
description | The route of transmission of Novel SARS-CoV-2 virus is ambiguous. In this regard we planned a study to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in serum and urine samples. We also report that SARS-CoV-2-RNA persisted in faeces for >20 days. Persistence of faecal RNA might impose challenge in infection control and the disease may spread to household contacts if discharged. Perineal cleaning and hygiene may be advised at the time of vaginal delivery. |
format | Online Article Text |
id | pubmed-7667402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Indian Association of Medical Microbiologists. Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76674022020-11-16 SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study Prakash, Shantanu Shukla, Suruchi Mishra, Hricha Prakash, Om Khan, Danish N. Pandey, Ajay Reddy, D. Himanshu Jain, Amita Indian J Med Microbiol Brief Communication The route of transmission of Novel SARS-CoV-2 virus is ambiguous. In this regard we planned a study to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in serum and urine samples. We also report that SARS-CoV-2-RNA persisted in faeces for >20 days. Persistence of faecal RNA might impose challenge in infection control and the disease may spread to household contacts if discharged. Perineal cleaning and hygiene may be advised at the time of vaginal delivery. Indian Association of Medical Microbiologists. Published by Elsevier B.V. 2021-01 2020-11-16 /pmc/articles/PMC7667402/ /pubmed/33610243 http://dx.doi.org/10.1016/j.ijmmb.2020.10.012 Text en © 2020 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Brief Communication Prakash, Shantanu Shukla, Suruchi Mishra, Hricha Prakash, Om Khan, Danish N. Pandey, Ajay Reddy, D. Himanshu Jain, Amita SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study |
title | SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study |
title_full | SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study |
title_fullStr | SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study |
title_full_unstemmed | SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study |
title_short | SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study |
title_sort | sars-cov-2 –rna persists longer in faecal sample as compared to nasal and throat swab samples of covid-19 patients’; an observational study |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667402/ https://www.ncbi.nlm.nih.gov/pubmed/33610243 http://dx.doi.org/10.1016/j.ijmmb.2020.10.012 |
work_keys_str_mv | AT prakashshantanu sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy AT shuklasuruchi sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy AT mishrahricha sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy AT prakashom sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy AT khandanishn sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy AT pandeyajay sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy AT reddydhimanshu sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy AT jainamita sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy |