Cargando…

SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study

The route of transmission of Novel SARS-CoV-2 virus is ambiguous. In this regard we planned a study to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in...

Descripción completa

Detalles Bibliográficos
Autores principales: Prakash, Shantanu, Shukla, Suruchi, Mishra, Hricha, Prakash, Om, Khan, Danish N., Pandey, Ajay, Reddy, D. Himanshu, Jain, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Association of Medical Microbiologists. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667402/
https://www.ncbi.nlm.nih.gov/pubmed/33610243
http://dx.doi.org/10.1016/j.ijmmb.2020.10.012
_version_ 1783610305363836928
author Prakash, Shantanu
Shukla, Suruchi
Mishra, Hricha
Prakash, Om
Khan, Danish N.
Pandey, Ajay
Reddy, D. Himanshu
Jain, Amita
author_facet Prakash, Shantanu
Shukla, Suruchi
Mishra, Hricha
Prakash, Om
Khan, Danish N.
Pandey, Ajay
Reddy, D. Himanshu
Jain, Amita
author_sort Prakash, Shantanu
collection PubMed
description The route of transmission of Novel SARS-CoV-2 virus is ambiguous. In this regard we planned a study to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in serum and urine samples. We also report that SARS-CoV-2-RNA persisted in faeces for >20 days. Persistence of faecal RNA might impose challenge in infection control and the disease may spread to household contacts if discharged. Perineal cleaning and hygiene may be advised at the time of vaginal delivery.
format Online
Article
Text
id pubmed-7667402
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Indian Association of Medical Microbiologists. Published by Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-76674022020-11-16 SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study Prakash, Shantanu Shukla, Suruchi Mishra, Hricha Prakash, Om Khan, Danish N. Pandey, Ajay Reddy, D. Himanshu Jain, Amita Indian J Med Microbiol Brief Communication The route of transmission of Novel SARS-CoV-2 virus is ambiguous. In this regard we planned a study to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in serum and urine samples. We also report that SARS-CoV-2-RNA persisted in faeces for >20 days. Persistence of faecal RNA might impose challenge in infection control and the disease may spread to household contacts if discharged. Perineal cleaning and hygiene may be advised at the time of vaginal delivery. Indian Association of Medical Microbiologists. Published by Elsevier B.V. 2021-01 2020-11-16 /pmc/articles/PMC7667402/ /pubmed/33610243 http://dx.doi.org/10.1016/j.ijmmb.2020.10.012 Text en © 2020 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Communication
Prakash, Shantanu
Shukla, Suruchi
Mishra, Hricha
Prakash, Om
Khan, Danish N.
Pandey, Ajay
Reddy, D. Himanshu
Jain, Amita
SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study
title SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study
title_full SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study
title_fullStr SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study
title_full_unstemmed SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study
title_short SARS-CoV-2 –RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational study
title_sort sars-cov-2 –rna persists longer in faecal sample as compared to nasal and throat swab samples of covid-19 patients’; an observational study
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667402/
https://www.ncbi.nlm.nih.gov/pubmed/33610243
http://dx.doi.org/10.1016/j.ijmmb.2020.10.012
work_keys_str_mv AT prakashshantanu sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy
AT shuklasuruchi sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy
AT mishrahricha sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy
AT prakashom sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy
AT khandanishn sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy
AT pandeyajay sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy
AT reddydhimanshu sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy
AT jainamita sarscov2rnapersistslongerinfaecalsampleascomparedtonasalandthroatswabsamplesofcovid19patientsanobservationalstudy