Development of Nonbacterial Thrombotic Endocarditis While on Systemic Anticoagulation in Pancreatic Cancer: A Case Report

Nonbacterial thromboembolic endocarditis (NBTE), or marantic endocarditis, is a rare complication associated with advanced cancer. Enoxaparin or unfractionated heparin is considered the standard treatment for NBTE. In this case report, we describe a 59-year-old female with metastatic pancreatic canc...

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Autores principales: Wang, Jiasheng, Monga, Natasha, Mopala, Prashanth, Husnain, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667603/
https://www.ncbi.nlm.nih.gov/pubmed/33209525
http://dx.doi.org/10.7759/cureus.10967
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author Wang, Jiasheng
Monga, Natasha
Mopala, Prashanth
Husnain, Muhammad
author_facet Wang, Jiasheng
Monga, Natasha
Mopala, Prashanth
Husnain, Muhammad
author_sort Wang, Jiasheng
collection PubMed
description Nonbacterial thromboembolic endocarditis (NBTE), or marantic endocarditis, is a rare complication associated with advanced cancer. Enoxaparin or unfractionated heparin is considered the standard treatment for NBTE. In this case report, we describe a 59-year-old female with metastatic pancreatic cancer who presented with embolic stroke and was found to have new NBTE of the mitral valve while she was receiving the therapeutic dose of enoxaparin. Of note, her recent echocardiogram one week ago was negative for mitral valve vegetations. Our case emphasized that for patients with advanced cancer presenting with stroke, the diagnosis of NBTE should be entertained even for those on systemic anticoagulation.
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spelling pubmed-76676032020-11-17 Development of Nonbacterial Thrombotic Endocarditis While on Systemic Anticoagulation in Pancreatic Cancer: A Case Report Wang, Jiasheng Monga, Natasha Mopala, Prashanth Husnain, Muhammad Cureus Cardiology Nonbacterial thromboembolic endocarditis (NBTE), or marantic endocarditis, is a rare complication associated with advanced cancer. Enoxaparin or unfractionated heparin is considered the standard treatment for NBTE. In this case report, we describe a 59-year-old female with metastatic pancreatic cancer who presented with embolic stroke and was found to have new NBTE of the mitral valve while she was receiving the therapeutic dose of enoxaparin. Of note, her recent echocardiogram one week ago was negative for mitral valve vegetations. Our case emphasized that for patients with advanced cancer presenting with stroke, the diagnosis of NBTE should be entertained even for those on systemic anticoagulation. Cureus 2020-10-15 /pmc/articles/PMC7667603/ /pubmed/33209525 http://dx.doi.org/10.7759/cureus.10967 Text en Copyright © 2020, Wang et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Wang, Jiasheng
Monga, Natasha
Mopala, Prashanth
Husnain, Muhammad
Development of Nonbacterial Thrombotic Endocarditis While on Systemic Anticoagulation in Pancreatic Cancer: A Case Report
title Development of Nonbacterial Thrombotic Endocarditis While on Systemic Anticoagulation in Pancreatic Cancer: A Case Report
title_full Development of Nonbacterial Thrombotic Endocarditis While on Systemic Anticoagulation in Pancreatic Cancer: A Case Report
title_fullStr Development of Nonbacterial Thrombotic Endocarditis While on Systemic Anticoagulation in Pancreatic Cancer: A Case Report
title_full_unstemmed Development of Nonbacterial Thrombotic Endocarditis While on Systemic Anticoagulation in Pancreatic Cancer: A Case Report
title_short Development of Nonbacterial Thrombotic Endocarditis While on Systemic Anticoagulation in Pancreatic Cancer: A Case Report
title_sort development of nonbacterial thrombotic endocarditis while on systemic anticoagulation in pancreatic cancer: a case report
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667603/
https://www.ncbi.nlm.nih.gov/pubmed/33209525
http://dx.doi.org/10.7759/cureus.10967
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